Scientist, Biologics Analytical Development
- Employer
- Nektar Therapeutics
- Location
- San Francisco, CA, United States
- Start date
- Jul 11, 2019
View more
- Discipline
- Information Technology, Business/Data Analytics, Science/R&D, Biotechnology
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
- Hotbed
- Biotech Bay
Job Details
The Scientist, Biologics Analytical Development, is part of Nektar's Biologics CMC organization.
This role will be responsible for product characterization, analytical method development/validation of proteins and protein-conjugates for Nektar Biologic products in pre-clinical and clinical development stages. Conducts and collaborates with others on analytical issues relevant to long-term objectives and concerns. Develops testing methodologies to support process development of drug substance and drug product. This position contributes to and supports the company's research development and manufacturing to create high value therapeutics to address unmet medical needs.
The successful candidate will be responsible for:
- Developing and validating analytical methods to support early stage drug development activities
- Characterization of protein polymer conjugates to elucidate conjugate sites and distribution
- Assist Process Development Scientists in characterizing and monitoring in-process purification
- Transfering analytical methods to internal QC group or CROs for drug substance and drug product release testing
- Summarizing experimental data and writing technical reports
Requirements:
Requires a PhD in a scientific discipline and a minimum of 2 years related experience, may include post-doctoral experience. Exceptional non-PhDs with demonstrated capabilities and/or significant experience may also be considered. Must have in-depth knowledge and hands-on experience in analytical method development and characterization for biologics Must have extensive experience in different HPLC separation methods such as ion exchange, reversed phase, and size exclusion chromatography for proteins. Must be able to demonstrate potential for technical proficiency, scientific creativity, collaboration with others and independent thought. Must be able to clearly communicate scientific information both written and oral. Experience in mass spectrometry and capillary electrophoresis analysis of proteins is highly desirable. Works on problems of moderate scope in which analysis of situation or data requires a review of identifiable factors. Experience in technology transfer to internal QC lab or CRO in support of drug substance/drug product release testing is highly desirable. Good computer skills are required. Working knowledge of MS word, Excel, Power point is a plus. Must be willing to work as part of a team.
We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
Company
Nektar Therapeutics is a research-based development stage biopharmaceutical company that discovers and develops innovative medicines in areas of high unmet medical need. Our R&D pipeline of new investigational drugs includes treatments for cancer and auto-immune disease. We leverage Nektar's proprietary and proven chemistry platform in the discovery and design of our new drug candidates. Our success is rooted in four key elements: our track record reflected by a portfolio of successful approved medicines which emanated from our chemistry platform and are made available globally by our pharmaceutical partners, our unique research and development pipeline of new investigational medicines in cancer and immunology, our proprietary and proven science and technology approach that fuels our discovery efforts and our team of dedicated scientists, clinicians and employees focused on bringing new medicines to patients with debilitating diseases.
Stock Symbol: NKTR
Stock Exchange: NASDAQ
- Website
- http://www.nektar.com/
- Phone
- 415-482-5300
- Location
-
455 Mission Bay Blvd South
San Francisco
California
94158
United States
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