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Bioinformatician

Employer
Gladstone Institutes
Location
San Francisco, CA
Start date
Jul 10, 2019

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Discipline
Science/R&D, Bioinformatics, Biostatistics
Required Education
Masters Degree/MBA
Position Type
Full time
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Job Details

Overview

The Gladstone Institutes is an independent, not-for-profit research institution. Its mission is to improve the health and well-being of all people through medical research and education in neuroscience, cardiovascular biology, immunology, and stem cell biology. Home to notable leaders in science and biomedicine, Gladstone comprises four institutes as well as various centers and programs. All of its approximately 500 members are aligned in their mission to carry out or support science that overcomes disease. Located in an award-winning building at the Mission Bay Campus, Gladstone offers a competitive salary and benefits program. It provides an ideal environment for those seeking to maximize and fully leverage their potential. Please consider Gladstone and make a difference in human health.

Responsibilities

The Biofulcrum Initiative at Gladstone/UCSF seeks a Bioinformatician. The candidate will be responsible for collaborating with multiple researchers in the Initiative and participating in the experimental and statistical design of projects, and in the biological interpretation and integration of the resulting complex data sets.

The candidate will be responsible for applying the appropriate algorithms, computational and modeling techniques, and statistical methodologies to analyze and visualize data primarily generated through high-throughput proteomics experiments, genome-wide CRISPR-Cas9 editing, as well as ChIP-seq, ATAC-seq, and single cell RNA-seq experiments. The candidate is expected to create and maintain effective proteomics and genomics databases, perform comprehensive pathway-analysis and develop/maintain web-based tools for disseminating information to collaborators. The candidate will also have the opportunity to develop novel pipelines for analyzing and interpreting proteomics and genomics data, and integrating it with other types of data.

Requirements

Qualifications

Required qualifications:
  • M.S in bioinformatics, statistics, mathematics, computer science or a related discipline
  • 2+ years of relevant research experience in generalized and/or linear mixed models, machine learning algorithms, experimental design, general statistical, and other commonly applied techniques in statistical omics data analysis.


Preferred qualifications:
  • PhD in bioinformatics, statistics, mathematics, computer science or a related discipline together with relevant research experience in generalized and/or linear mixed models, machine learning algorithms, experimental design, general statistical, and other commonly applied techniques in statistical omics data analysis.
  • Understanding of large-scale proteomics and genomics data and placing it in a biological context, as well as experience working with other -omics data such as transcriptomics, lipidomics, and metabolomics.
  • Strong computational skills and prior experience with Unix/Linux and Windows environments, as well as programming, creating applications and packages in R.
  • Skill in relational database design, implementation, optimization, and storage procedures.
  • Experience with programming language preferred such as C/C++, Java, Python, and .NET, and familiarity with data visualization tools and in GUI development.
  • Ability to develop web sites and set up effective sharing of data and analysis tools.
  • Team player able to work in large collaborative projects.

PI111757397

Company

Gladstone is an independent, nonprofit life science research organization located in the epicenter of biomedical and technological innovation in the San Francisco Bay Area. Gladstone has created a research model that disrupts how science is done, funds big ideas, and attracts the brightest minds. Gladstone Institutes leads the way for innovative research in the biomedical field. We always seek dedicated and talented individuals to join our team.

Scientists know that using a diversity of approaches is often the most efficient strategy for solving a problem. New and different perspectives engender the very innovation that Gladstone prizes. This is one of the many reasons why we value diversity at Gladstone—be that a diversity of race, culture, religion, mental or physical ability, heritage, age, gender, sexual orientation or other characteristics. Our employees hail from more than 30 countries around the globe and we seek to hire the best and brightest for our diverse team of scientists and administrators. Career opportunities are available in both our administrative offices and our research areas.

Our Benefits
Gladstone offers eligible employees—and their dependents—a comprehensive range of benefits, including health insurance, retirement savings, and professional development.

Highlights

  • Health and Retirement
    • A choice of medical plans, flexible spending account, and retirement account options that include employer contributions help you take care of your health and your future.
  • Time Away from Work
    • More than just vacation days, our paid and unpaid leave policies offer flexibility to help you confront different stages of life including maternity and paternity leave, as well as other types of family leave.
  • Professional Development
    • Gladstone encourages employees to seek the skills they need to remain at the forefront of their profession. By supporting professional development workshops and continuing education, Gladstone provides employees with the resources they need to evolve in their role and in their career.
  • Gladstone Cares
    • A specially selected suite of benefits to support you in and out of the workplace. Includes resources for dealing with the many stages of life to specific coverage for family planning, and back-up child or elder care coverage.
Company info
Website
Location
1650 Owens Street
 San Francisco
California
94158
United States
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