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Research Associate - Fermentation, Protein Sciences

Employer
Molecular Templates, Inc.
Location
Austin, TX, USA
Start date
Jul 8, 2019

View more

Discipline
Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time

Job Details

Company Description:

Molecular Templates (MTEM) is a clinical stage biopharmaceutical company targeting a variety of cancers through development of its innovative proprietary Engineered Toxin Body (ETB) platform. MTEM's first immunotoxin, MT-3724, is in clinical development for non-Hodgkin's lymphoma. Pipeline products for additional oncology targets are being advanced toward clinical development. For more information, please visit MTEM's website at www.mtem.com.

Position Overview:

Molecular Templates is seeking a highly-motivated and skilled Research Associate to support upstream processing for Protein Sciences. This position will perform functions related to production of pre-clinical drug product and early-stage process development for protein sciences, including routine protein expression, equipment maintenance checks and calibration, data management, and assist in review and development methods and procedures to control or modify the process. This position will also aid in identifying continuous process improvement areas. This will require excellent technical, analytical and organizational skills, along with adherence to written and verbal instructions and accurate and timely completion of manufacturing batch records.

Job Responsibilities will include:
  • Perform protein expression for production of pre-clinical drug product and early-stage process development for protein sciences, includes, but not limited to: cell culture, cell banking, bioreactor operation, cell plating, cell harvesting, media preparation, equipment cleaning and sterilization, process data recording and trending.
  • Conduct limited characterization of metabolic products and protein expression using common laboratory techniques.
  • Complete required documentation in an accurate and timely manner, adhering to written procedures and regulatory requirements.
  • Review and revise established protocols and SOPs related to drug development, such as process development and optimization techniques. This may also include developing and optimizing assays, conducting limited literature search of research study protocols and reports, regulatory documents, and other potential resources.
  • Conduct general laboratory duties, including washing glassware, ordering supplies, and maintaining inventory (e.g. buffer) and basic laboratory equipment
  • Assist with non-complex projects, such as laboratory sanitization and organization or implementation of new instrumentation, as needed


Qualifications:
  • Bachelor's degree in Life Sciences or equivalent
  • Minimum of one (1) year relevant experience in laboratory setting conducting or supporting protein expression methods
  • Demonstrated experience and comprehensive knowledge of protein expression, required
  • Experience with microbial fermentation using bioreactor (5L/10L) or cell culture fermentation, preferred
  • Experience in biopharmaceutical industry, preferred
  • Excellent written and verbal communication skills
  • Excellent computer skills with knowledge of spreadsheet and word processing
  • Excellent problem-solving and analytical skills applied to investigations
  • Excellent organizational, time management and multi-tasking skills
  • Ability to follow written and verbal instruction and work under supervision
  • Ability to work in a fast-paced, team environment
  • Ability to regularly lift and/or move up to 50 pounds manually or with additional assistance from staff and/or mechanical lifting equipment (e.g. dolly, cart, lift, hand truck, etc.) to a shelf located 4-6 feet in height; Stand for long periods of time; Bend twist, push/pull, crouch, kneel.


Reporting Structure:

This position has no supervisory responsibilities. This position reports to the Sr. Manager, Protein Sciences, R&D.

Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.

Molecular Templates Inc https://mtem.isolvedhire.com

Company

Molecular Templates, Inc. (MTEM) is a clinical stage biopharmaceutical company focused on the discovery and development of biologic therapeutics for the treatment of cancer and other serious diseases. The company primarily develops a pipeline of therapies through its proprietary biologic engineered toxin body (ETB) drug platform with unique mechanisms of actions which are highly differentiated from antibody drug conjugates (ADCs). MTEM is developing MT-6402, which is in a Phase I clinical trial for PD-1/PD-L1 antibody relapsed/refractory patients; MT-5111, which is in a Phase I clinical trial for the treatment of HER2-positive cancers; and MT-0169, which is in a Phase I clinical trial to treat relapsed/refractory myeloma. Additional preclinical compounds derived from our ETB platform technology are being advanced toward clinical development.  Additional information about MTEM can be obtained at www.mtem.com.  

OWNERSHIP: Public

STOCK SYMBOL: MTEM

STOCK EXCHANGE: NASDAQ

Company info
Website
Phone
512-869-1555
Location
9301 Amberglen Blvd, Ste 100
Austin
TX
78729
US

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