Drug Discovery - Postdoctoral Scientist - Cedars-Sinai Cancer

Location
Los Angeles, CA
Posted
Jul 03, 2019
Ref
19002007
Required Education
Doctorate/PHD/MD
Position Type
Full time

Cedars-Sinai Medical Center ranks among the nation's top ten non-university hospitals receiving federal funding for research and currently has more than 1,500 active research projects. Cedars-Sinai Cancer supports basic and clinical research in many areas and researchers are seeking more effective ways to diagnose, treat and prevent many forms of cancer.

Postdoctoral scientist opportunities are available in the Theodorescu laboratory at Cedars-Sinai.  Dr. Theodorescu is a nationally recognized translational cancer researcher and Principal Investigator of an NIH/NCI-funded laboratory, leading expert in bladder cancer, and newly appointed Director of Cedars-Sinai Cancer. The postdoctoral scientists will work independently on research projects under the supervision of the principal investigator. 

Theodorescu Lab | Drug Discovery The Theodorescu lab has made significant contributions in the area of drug discovery. These contributions include discovery and development of a “first in class” RalGTPase inhibitor as a new therapeutic in several human cancer types (Nature. 2014 20;515(7527):443-7). Using functional genomics screens and transcriptomics on human cell lines and tumor tissues, we have identified several candidate genes that confer resistance to commonly used chemotherapeutics in bladder cancer and other tumors. We are seeking a highly motivated individual to further develop this work by defining the mechanism of action of how these genes alter resistance to such drugs such as cisplatinum, gemcitabine and others including small molecules.  (Requisition #19002007)

The Theodorescu Lab also has an Immunology (job # 19002028) and Telomerase Biology postdoctoral scientist positions (job ##19002008).

The successful candidates will have a PhD degree in molecular biology, cell biology, immunology, biochemistry or related field. Candidate may be recent PhD recipients or individuals seeking additional postdoctoral training. Strong preference will be given to individuals with proven track record of productivity.

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