Cell Line Development Scientist
- Employer
- Kashiv BioSciences, LLC
- Location
- 08854, Piscataway
- Start date
- Jun 27, 2019
View more
- Discipline
- Science/R&D, Bioanalytical Services, Bioengineering, Biomedical Sciences, Biotechnology, Cell Biology, Research, Laboratory, Molecular Biology
- Required Education
- Bachelors Degree
- Position Type
- Full time
Position Summary
Kashiv BioSciences A fully-integrated biosciences company with an expanded and dynamic platform for growth including advanced drug delivery technologies, biosimilars, prodrugs, and a large development pipeline. We are looking for an experienced Cell Line Development Scientist to join our Piscataway, NJ process development team. Please visit http://kashivbiosciences.com/ for more information about Kashiv BioSciences.
The Cell Line Development Scientist will be responsible for generating high producing mammalian cell lines for recombinant protein production. These cell lines will be used for preclinical, clinical and commercial biosimilar manufacturing. The candidate will be responsible for the cell line development design and execution activities. The position will also be involved in upstream cell culture process development and other project-related activities. This position requires technical expertise in molecular biology, cell biology, understanding of regulatory requirement for manufacturing cell line and working knowledge in bioprocess development.
Essential Duties & Responsibilities
- Prepare, select, and develop mammalian cell lines for recombinant protein production
- Optimize mammalian expression plasmid vector sequences to improve transcription efficiency, mRNA stability, and recombinant protein expression
- Analyze target products using standard and high throughput assays
- Support upstream process development activities
- Performs other functions as required or assigned
- Complies with all company policies and standards
Position Requirements and Qualifications
Education:
- Bachelor’s, Master’s degree, or Doctoral degree in chemical, biological, or biochemical sciences with at least 5 years of experience (2 years for PhD) in the biopharmaceutical industry
- Industry based stable cell line development experience
- In-depth understanding and demonstrated experience in modifying - vectors, sub-cloning of cDNAs into vectors, and associated molecular biology techniques
Special Skills:
- Familiarity with flow cytometry (FACS), automated - cell imaging system, basic antibody characterization assays, and high throughput screening
- Experience in cell culture media and feed development is a plus
Work Environment & Physical Demands:
General work environment and physical demands as required to successfully perform the essential functions of this job. Ability to work flexible hours as needed. Ability to work under pressure and meet deadlines. Some travel may be involved.
Supervisory Responsibility, if any: No/Yes
This position description is not a complete list of all responsibilities, duties or skill required for the job and is subject to review and change at any time, with or without notice, in accordance with the needs of the organization.
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