Scientist/Sr. Scientist, Pharmacology

Adicet is developing the next generation immunotherapies by generating a pipeline of allogeneic gamma delta T cell products engineering with CAR or TCR. In addition,
Adicet's immune cell platform is complemented by its ability to identify and validate novel disease specific peptide-MHC targets and generates T cell receptor-like antibodies directed against these disease-specific peptide MHC complexes.
Adicet Bio was founded in late 2015 and closed a Series A financing of $51M in Jan 2016. This financing was led by OrbiMed and also included Novartis Venture Funds and Pontifax. In August 2016, Regeneron and Adicet Bio announced a strategic collaboration to discover and develop next-generation engineered immune-cell therapeutics, for which Adicet received a $25M upfront payment.

In September 2016, Adicet Bio was recognized and named by FierceBiotech to its "Fierce 15" Biotech Companies of 2016.

SCIENTIST/SENIOR SCIENTIST, PHARMACOLOGY

We are currently seeking a highly motivated candidate with a strong immunology background to join our pharmacology team.

KEY RESPONSIBILITIES:

• Work closely with multiple functional groups in the efforts to progress immune cell-based cancer therapies to the clinic.
• Design, conduct, and manage in vivo and ex vivo experiments to evaluate Adicet's immune cell platforms, such as anti-tumor efficacy, in vivo phenotyping, cell trafficking, distribution and persistence in animal models.
• Support biomarker discovery and translational studies for Adicet's clinical candidates through in vivo
• Perform hands-on work when needed, including animal model handling, in vivo data collection and ex vivo analyses of blood and organ/tumor tissues.
• Manage and analyze experimental data, interpret results and prepare presentations for internal and external meetings, regulatory filings and publications.
• Provide scientific inputs and contribute intellectually to the organization success.
• Manage and direct daily work of junior research staff.
• Maintain detailed documentation of procedures and data to comply with internal quality criteria.

QUALIFICATIONS:

• PhD in Immunology or relevant biological sciences with an immuno-oncology research background.
• A minimal two years of postdoctoral research experience, preferably in an industry setting.
• Previous hands-on experience in murine tumor models including xenograft and/or syngeneic models is required.
• Must demonstrate experience in establishing, executing and interpreting in vivo experiments in oncology research and technical excellence in murine tumor models.
• Experience in ensuring quality studies and accurate analysis of in vivo data is required.
• Previous hands-on experience in multi-color flow cytometry and independently analyzing the data using analytical software such as FlowJo is required.
• Previous hands-on experience in in vivo bioluminescence and/or fluorescence imaging workflow and data analysis is preferred.
• Experience in working knowledge of immunohistochemistry and data interpretation is a plus.
• Demonstrate scientific creativity, critical thinking, and analytical problem-solving skills, with a strong track record of research productivity as evidenced by high-quality publications.
• Ability to work efficiently and independently under minimal supervision in a dynamic team environment.
• Previous management experience is preferred.
• Excellent written and verbal communication skills.

BENEFITS:

Adicet Bio offers both comprehensive benefits and Paid Time (PTO) plans for employees, which begin on the first day of employment, as well as the opportunity to work in a growing, dynamic environment.

Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.