Associate Scientist I/II, Cell Biology and Molecular Neuroscience

Cambridge, MA, US
Jun 25, 2019
Required Education
Masters Degree/MBA
Position Type
Full time
AbbVie has established the Foundational Neuroscience Center (FNC) in Cambridge, MA to investigate the fundamental biological mechanisms and to develop therapeutic interventions for neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. The Tau Biology group is seeking a highly motivated applicant with prior experience and expertise in cell biology and molecular neuroscience for target validation and assay development in neuroscience. The Scientist will support a project leader in performing molecular and multiplexed image-based screening studies to discover small molecules/biologics interfering with tau aggregation/propagation in neurons.

Key Responsibilities Include:

  • Perform research in a dynamic and collaborative environment
  • Support identification and validation of targets using cell biology and molecular techniques
  • Experience in cell signaling, neuropharmacology
  • Work efficiently to meet deadlines, well with team members, and contribute to a healthy and fast-paced environment.
  • Lead and or / assist in writing SOPs
  • Excellent communication - both in writing and presenting results with direct report and team, analytical, and interpersonal skills.
  • Read and apply relevant scientific literature

Position will be hired based on level of experience.

  • Bach elors or Masters in Molecular Neuroscience or related field with typically 0-4+ (BS) or 0+ (MS) years' experience; Pharmaceutical industry experience preferred.
  • Proficiency with cell biology, molecular biology.
  • Expertise in cellular assays for target validation and high throughput screening.
  • Experience in molecular neuroscience fields such as neuropharmacology, learning and memory
  • Experience of working with mRNA is preferred but not required
  • Experience in primary neuronal tissue culture. Human iPSC-derived neuron is a plus but not required.
  • Experience with super-resolution, high - content, high throughput using robotic-assisted imaging is a plus but not required.
  • Familiarity with plate readers and/or high content imaging / familiarity with neuroanatomy is plus but not required.
  • Comfortable using computer programs such as Microsoft, PowerPoint, Google Docs, Microsoft Excel
  • Highly motivated, detailed oriented, curious of the science, and desire to learn to novel neuroscience techniques.
  • Demonstrate critical thinking, independence, clear scientific writing & verbal communication skills and precise record keeping
  • Strong organizational skills that facilitate planning, multitasking and working within timelines.