Amgen

Scientist

Employer
Amgen
Location
Thousand Oaks, CA, US
Posted
Jun 25, 2019
Ref
R-78839
Required Education
Bachelors Degree
Position Type
Full time
In our mission to serve patients, speed is absolutely critical. We're rapidly expanding our hiring initiatives and are excited to unite with the most passionate and brilliant scientific minds who want to join our team - working toward our mission of advancing high potential programs for patients around the world.

Amgen is seeking a Scientist-Clinical Pharmacology, Modeling and Simulation who will be located in our Thousand Oaks, CA location. As part of the Clinical Pharmacology, Modeling and Simulation department, the Modeling and Simulation Scientist will support Amgen clinical development and translational sciences programs across multiple therapeutic areas with emphasis on oncology.

Responsibilities of the Scientist include:
  • Building pharmacostatistical models to support Population Pharmacokinetics/Pharmacodynamic (PKPD) and exposure-response analyses using relevant state of the art modeling and simulation techniques.
  • Training in binary and categorical and binary data analyses, time-to-event (hazard) models, Poisson models, MCMC and Bayesian methods as applied to exposure-response analyses and Population PK and PKPD analysis.
  • Perform meta-analysis using proprietary and/or literature data.
  • Participate in cross-functional project teams and provide scientific input for dose selection, early and late study designs using modeling and simulation inputs.
  • Contribute to clinical pharmacology strategy for the program(s) and implement project plans.
  • Generate modeling reports and contribute to the summary documents for regulatory submissions.


Basic Qualifications:

Doctorate degree

OR

Master's degree and 4 years of scientific experience

OR

Bachelor's degree and 6 years of scientific experience

Preferred Qualifications:
  • PhD, MD or PharmD in pharmaceutical sciences, applied statistics/mathematics, biostatistics, and/or engineering
  • 2+ years industry or relevant academic experience in pharmacometric analyses and/or applied biostatistics of small molecules and/or biologics.
  • Proficiency in modeling software (e.g. NONMEM, R, SAS, STAN, MATLAB)


We understand that to successfully sustain and grow as a global enterprise and deliver for patients - we must ensure a diverse and inclusive work environment.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

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