Research Scientist In-Vivo Pharmacology
- Employer
- Bristol Myers Squibb Company
- Location
- Cambridge, MA, United States
- Start date
- Jun 22, 2019
View more
- Discipline
- Science/R&D, Biotechnology, Pharmacology
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Genetown, Best Places to Work
Job Details
The In Vivo Pharmacology Research Scientist will join the Oncology Discovery Pharmacology and In Vivo Biology group at Bristol-Myers Squibb in Cambridge, MA. The individual hired for this position will conduct experiments utilizing tumored mouse or rat models to aide in the advancement of early stage therapeutic targets at the intersection of tumor genetics and tumor immunobiology.
The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment to advance preclinical drug development programs from target identification/validation through IND enabling activities.
Qualifications
- A B.S. with a minimum of 7 years, or an M.S. with a minimum of 5 years of leveraging in vivo pharmacology models to explore cancer biology and enable drug discovery is required.
- Demonstrated experience independently running and analyzing data from in vivo xenograft or syngeneic tumor efficacy and PK/PD studies is required.
- Required skills include: tumor model development, dosing (IV, IP, SC, I-TUMOR and PO routes), tumor measurements by caliper, blood collection and tissue/tumor collection at necropsy
- Proficiency in cell culture is required.
- Experience with ex vivo techniques such as qPCR, ELISA (MSD), or WB is highly desired.
- Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation is required.
- Ability to mentor junior scientists and colleagues on best practices in the laboratory would be highly valued.
- Attention to detail with excellent organizational and record keeping skills is a requirement.
Responsibilities include:
- Independently conduct and analyze xenograft and syngeneic in vivo efficacy and PK/PD studies
- Mentor junior associates on best practices (in vivo and ex vivo)
- Utilize ELISAs (MSD), qPCR, or WB to monitor biomarkers in harvested tissues
- Accurately maintain proper scientific documentation of experiments and associated data in an electronic lab notebook.
- Effectively communicate and present summaries of research results to team members.
- This position is located in Cambridge, MA.
Company
Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.
At Bristol Myers Squibb, we believe in the power of science to address some of the most challenging diseases of our time. Our focus on these unmet needs comes during a remarkable time, when unprecedented scientific breakthroughs are advancing the treatment of disease as never before in human history.
We work every day to transform patients’ lives through science. Each day, our employees around the world work together for patients – they are at the center of everything we do. They inspire us. They are the reason we come to work each day.
We combine the agility of a biotech with the reach and resources of an established pharmaceutical company to create a global leading biopharma company powered by talented individuals who drive scientific innovation.
- Website
- http://www.bms.com/
- Phone
- +1-800-332-2056
- Location
-
430 E. 29th St
14th Floor
New York
New York
10016
United States
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