Research Associate (Discovery Biology)

South San Francisco, CA, United States
Jun 19, 2019
Biotech Bay
Required Education
Associate Degree
Position Type
Full time
Research Associate (Discovery Biology)

Neurona Therapeutics is an early stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for neurological disease. Our ideal candidate is a self-motivated individual who has a passion for scientific research. This is a fantastic opportunity to join a small team, work on transformative science, and take part in building an exciting, science-driven company.

Responsibilities include:
  • Maintain human pluripotent stem cells and differentiated cells.
  • Perform stem cell differentiation into neuronal lineages using a large variety of formats, from 384 well plates to regular and large scale culture vessels.
  • Develop screening cell based assays using automated liquid handler for stem cell differentiation optimization.
  • Utilize High Content Screening (HCS) technology for high-throughput analysis of cell populations.
  • Characterize differentiated cells using a panel molecular biology methods (immuno cyto-chemistry, Flow cytometry, RT-QPCR).
  • Conduct fluorescence or magnetic -activated cell sorting experiments.
  • Prepare tissue culture reagents (media, small molecules, cytokines); Tissue culture room upkeep and restocking.
  • Maintain detailed records.

Required Qualifications:
  • Bachelor's degree (+2 years of relevant experience) or Master degree in cell/molecular biology or related field.
  • Clear knowledge of sterile tissue culture technique (at least two years experience).
  • Familiar with pluripotent stem cell culture, in vitro directed differentiation paradigms and molecular/functional characterization of derived cell types.
  • Experience with automated liquid handlers to perform medium / high throughput cell based screenings
  • Willing to work a limited number of hours during weekends.
  • Excellent writing, verbal communication, and interpersonal skills.
  • Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance research productivity.

Preferred Qualifications:
  • At least one year of experience with human pluripotent (embryonic or induced) stem cell maintenance, differentiation, cell sorting and immuno cyto chemistry.
  • One year of experience with lab automation for cell based screening assays using liquid handling automates (protocol creation, hands on automates)
  • Experience with transcript- and protein-based gene expression analyses, high content screening.
  • Knowledge of human developmental biology.