Amgen

Scientist - Oncology Research

Employer
Amgen
Location
Thousand Oaks, CA, US
Posted
Jun 18, 2019
Ref
R-66575
Required Education
Bachelors Degree
Position Type
Full time
The Department of Oncology Research at Amgen, Thousand Oaks seeks an exceptional and motivated Scientist to lead and contribute to programs focused on the discovery and development of targeted oncology therapeutics. As part of a cross functional team, the successful candidate will be responsible for discovering new target biology and will lead or provide support to collaborative cross functional drug discovery project teams

Key responsibilities will include:
  • In collaboration with our bioinformatics team, lead and contribute to new target identification and validation using genomic approaches such as CRISPR to assess gene function
  • Drive and provide key support to efforts to assess the pharmacodynamic activity, efficacy and mechanism of action of therapeutic candidates in preclinical oncology models
  • Close collaboration with our biomarker scientists to develop and implement pharmacodynamic assays and patient stratification strategies for programs transitioning to clinical development
  • Partner with colleagues in the oncology therapeutic area, bioinformatics and medicinal chemistry to develop strategy and new technologies to achieve our drug discovery goals
  • Represent project teams through presentations at internal and external forums and the submission of manuscripts for publication


Basic Qualifications

Doctorate degree

OR

Master's Degree and 4 years of scientific experience

OR

Bachelor's Degree and 6 years of scientific experience

Preferred Qualifications
  • PhD and training in cancer biology or a related field
  • 2+ years postdoctoral experience in an academic or industry setting
  • Technical expertise with state of the art molecular and cell biology techniques, particularly those relevant for assaying gene function (e.g. CRISPR or shRNA)
  • Experience in target identification, validation and bioinformatics or experience supporting, or leading drug discovery programs
  • Evidence of independent critical thinking and scientific achievement, supported by a strong publication record and/or significant contributions to a drug discovery program.