Senior Scientist, Functional Immunology

Employer
AbbVie
Location
Cambridge, MA, US
Posted
Jun 15, 2019
Ref
1904067
Required Education
Bachelors Degree
Position Type
Full time
AbbVie Immunology is expanding its early discovery at Cambridge, Massachusetts. This new research group will focus on identifying new targets for the treatment of autoimmune and chronic inflammation diseases through computational analysis of human disease tissue derived datasets, and validating targets using in vitro and in vivo experimental approaches. We are seeking a highly skilled and dedicated individual to partner with Functional Genomics and bioinformatics expertise and in vivo pharmacologists to develop novel platforms for target screen and validation. This position requires passion, attention to details, hands-on experience and teamwork spirits.

Key Responsibilities Include:
  • Identify and lead individual target in early discovery to treat autoimmune disorders
  • Build data package for potential target by investigating target biology using CRISPR-based technology and tool molecules
  • Develop new immunological functional assays in vitro and in vivo
  • Participate in functional genetic screens; functionally rank the therapeutic potential of targets for Immunology therapeutic area
  • Analyze data and present work in internal meetings


  • BS, MS, or PhD in immunology or other biological sciences with typically 10+(BS), 8+(MS), or 0+ (PhD) years of post-doctoral experience
  • Good understanding of CRISPR and RNAi based technologies; hands-on experience doing genome editing using CRISPR preferred
  • Extensive experience in developing in vitro functional assays; experience with immunoassays including FACS, ELISA, cell-based assays preferred.
  • Excellent communication skills
  • Ability to work independently as well as to collaborate with peers
  • Knowledgeable in Immunology; experience working on immunology assays, FACS analysis, etc.
  • Familiar with animal models especially immunologic models

Key AbbVie Competencies:
  • Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance.
  • Learns fast, grasps the "essence" and can change the course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.