Senior Scientist - Oncology and Inflammation Biomarker Discovery

South San Francisco, CA, US
Jun 15, 2019
Required Education
Bachelors Degree
Position Type
Full time
Senior Scientist - Oncology and Inflammation Biomarker Discovery

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is developing a Biomarker-Discovery group to support therapeutic programs.

The Amgen Inflammation & Oncology Research Group is looking for a Scientist dedicated to biomarker discovery in the areas of immuno-oncology and inflammation. In this role you will work cross-functionally and interact closely with both the clinical biomarker and discovery research groups.

The position will focus on the discovery of biomarkers to support the progression of therapeutic candidates from discovery to early clinical development. The role is responsible for:
  • Developing deep disease area expertise for key indications in the therapeutic area's strategy
  • Discovery and prioritization of disease stratification and target engagement biomarker candidates relevant to the pipeline
  • Developing, implementing, and executing a therapeutic biomarker discovery strategy across several programs
  • Generating and transitioning key pharmacodynamic and patient stratification/selection biomarker discovery data in support of clinical biomarker assay and companion diagnostic test development
  • Supporting translational biomarker activities for therapeutic assets including investigator meetings/ad boards and investigator sponsored studies for correlative biomarker research together with the Clinical Biomarker lead

The role is expected to work in a highly matrixed environment to drive scientific and technical innovation collaboratively with other members of the Inflammation & Oncology group, as well as with other functions including the Clinical Biomarker & Diagnostics Team, Translational Medicine, Therapeutic Discovery, Human Genetics and Computational Biology.

Basic Qualifications

Doctorate degree and 2 years of scientific experience

Master's degree and 5 years of scientific experience

Bachelor's degree and 7 years scientific experience

Preferred Qualifications

PhD or MD, with postdoctoral training and research experience in the fields of immunology, oncology and/or cancer immunotherapy

Demonstrated track record of independent critical thinking and scientific achievement in the areas of immunology and/or oncology as demonstrated by multiple high impact publications

Demonstrated experience in leading independent research and drug development

Experience with implementing multiple technology platforms

Experience with computational biology

Strong verbal and written communication skills. Ability to collaborate and troubleshoot to solve problems

Experience working in teams and consistently delivering results