Senior Scientist I, DMPK, Proteomics Research

Employer
AbbVie
Location
Worcester, MA, US
Posted
Jun 01, 2019
Ref
1903797
Required Education
Masters Degree/MBA
Position Type
Full time
We are seeking a highly motivated scientist to join our proteomics research team at the DMPK department at Abbvie Research Center in Worcester, MA location.

Responsibility

This position is responsible for proteomics sample preparation, LC/MS instrument optimization and method/platform development to support active research projects across sites and for different therapeutic modalities. The successful applicant will also contribute to the development and implementation of novel proteomics data analysis strategy including next gen label free DDA and DIA proteomics.

This position will require industry-academic collaboration to develop cutting edge sample preparation and bioinformatic tools to solve challenging biological problems, including protease biologics and extracellular matrix biology.

Publish and present research result in peer-reviewed journal and in national level conferences.

Requirement:

  • PhD in Analytical Chemistry, Bioinformatics, or proteomics field.
  • Strong scientific background in mass spectrometry and proteomics
  • Extensive hands-on experience in biological sample preparation for proteomics analysis is a must.
  • Extensive hands-on experience in operating nano HPLC and hybrid high resolution mass spectrometer including Thermo LUMOS for proteomics sample analysis. Experience in operating other mass spectrometry platforms (Q-TOF, QQQ, etc.) is a plus.
  • Proficient on proteomics software including implementation and programing in R packages. Experience with large-scale data analysis and bioinformatics research using pathway analysis tools.
  • Experience with proteomics data analysis programming is a plus.
  • Proven track record of peer reviewed publications in the field of proteomics method development and application in biological science.
  • The ability to manage multiple projects in parallel, communicate clearly and effectively and build collaborative relationships is essential.