Research Associate, in vivo Pharmacology
- Employer
- Vividion Therapeutics, Inc.
- Location
- 92121, San Diego
- Start date
- May 31, 2019
View more
- Discipline
- Science/R&D, Biology, Biotechnology, Research, Immunology, Laboratory, Pharmacology
- Required Education
- Bachelors Degree
- Position Type
- Full time
Job Details
Vividion Therapeutics is seeking a highly-motivated Research Associate to contribute to the identification and development of novel small-molecule drugs. Vividion is a privately held biotechnology company based in San Diego that is leveraging an innovative and proprietary chemical proteomics platform to efficiently discover novel drugs in multiple areas including oncology and immunology.
As an early stage startup company, Vividion is looking for energetic and experienced candidates with a desire to work in a fast-paced and dynamic team environment. The successful candidate will provide in vivo support for pre-clinical drug development and discovery efforts.
Responsibilities include, but are not limited to:
- Execute pharmacokinetic / pharmacodynamic, target engagement, efficacy, or mechanism of action studies to support pre-clinical and discovery programs.
- Administer small molecule compounds to mice, measure endpoints (i.e., tumor volume, body weight) and collect blood/tissue for analysis.
- Perform in vitro cell culture and cell-based assays measuring target engagement and drug effect(s).
- Perform ex vivo assays on collected cells and tissues as needed.
- Work both independently and collaboratively as part of an in vivo pharmacology team.
- Collect, organize and present scientific/technical data internally and in project team meetings.
Experience and education requirements:
- BS with 5-7 years’ experience or MS with 3-5 years’ experience of in vivo in a biotechnology or pharmaceutical setting. Ideally the degree should be in Cancer Biology, Cancer Immunology, Pharmacology or related field.
- Rodent dosing routes (P.O., IV, IP), blood collection (sub mandibular, terminal cardiac, retro orbital), tumor implantation, necropsy, and tumor/organ collection are required.
- In vitro cell culture including culture of primary human cancer cells is required.
- Immuno-oncology experience is very highly desired.
- Rodent surgery experience is highly desired.
- Experience with flow cytometry as well as formalin fixation, paraffin embedding, sectioning, and immunohistochemistry is highly desired.
- Animal Husbandry, IACUC, and AALAC experience is highly desired.
- Candidates must have effective troubleshooting and problem-solving skills and possess excellent oral and written communication skills.
- Candidates must be a team player, strong individual contributor, flexible, and able to handle multiple tasks and deliver high quality results under tight timelines.
In addition to a competitive compensation package with stock options, Vividion also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, life, disability insurance. For consideration, please submit a pdf of your resume and cover letter referencing job RAPH209.06.01 to careers@vividion.com. Vividion Therapeutics, Inc. is an EEO employer.
Company
Vividion Therapeutics, Inc. is a biotechnology company focused on transforming the future of human health through the limitless creation of highly selective small molecule medicines that drug traditionally inaccessible targets. The company is advancing a broad, diversified pipeline of multiple, selective small molecule therapeutics for highly sought-after disease-causing target proteins in oncology and immunology. Founded in 2016, the company’s cutting-edge platform was spun out of the labs of Vividion’s scientific founders, a team of experts in chemical biology and synthetic chemistry from The Scripps Research Institute in La Jolla, CA. For more information, please visit www.vividion.com.
Leadership
CEO: Jeffrey S. Hatfield
CBO/President: Fred Aslan, M.D.
CSO: Bob Abraham, Ph.D.
Founders
Benjamin F. Cravatt, Ph.D.
Phil S. Baran, Ph.D.
Jin-Quan Yu, Ph.D.
Email us at careers@vividion.com or media@vividion.com
- Website
- http://www.vividion.com/
- Phone
- 858-345-4690
- Location
-
5820 Nancy Ridge Drive
San Diego
California
92121
US
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