Research Associate/Sr. Research Associate, Cell Biology

Location
94080, South San Francisco
Posted
May 30, 2019
Required Education
Doctorate/PHD/MD
Position Type
Full time

The qualified candidate will join a team focused on discovery of small molecule therapeutics. In this position you will support drug discovery efforts by providing cell biology expertise.

 Responsibilities:
 

  • Culture a variety of cancer cell lines and primary cells
  • Prepare assay reagents, compound serial dilutions
  • Develop and execute cell-based assays in 96-well or 384-well format
  • Analyze molecules’ mechanism of action utilizing flow cytometry, immunofluorescence, western, qPCR, apoptosis or other assays
  • Perform data analysis, reporting and integration with GraphPad Prism, Microsoft Office and other software packages
  • Contribute to or lead lab management activities

Qualifications and Experience:

  • BS or MS in related scientific discipline
  • 2-6 years of industry experience in cell biology
  • Extensive experience in cell culture and compound profiling
  • Proficiency in quantitative cell-based assays desired
  • Familiarity with liquid handling platforms would be a plus
  • Experience with protein analysis by ELISA, MSD ELISA, western, flow cytometry, immunofluorescence
  • Experience with DNA and RNA isolation, qPCR and other RNA analysis techniques
  • Experience with retroviral/lentiviral vectors for generation of stable cell lines and gene knockdown/knockout using shRNA/CRISPR technologies would be a plus
  • Excellent computer skills combined with data analysis
  • Must be detail oriented, well organized, and have strong communication skills
  • Able to independently troubleshoot and identify solutions to arising issues
  • Excellent teamwork skills and the ability to work in a fast-paced, multi-disciplinary environment
  • Excellent work ethic, self-motivated, driven, dependable, hardworking

About ORIC Pharmaceuticals:
ORIC Pharmaceuticals is a privately held oncology company focused on making cancer treatments more effective by addressing mechanisms of resistance. ORIC was founded by Drs. Charles Sawyers MD and Scott Lowe PhD, who have strong records of discovering innovative treatments and targets in cancer. The company has assembled strong leadership and scientific teams and a board with extensive experience in drug development and financing. ORIC is funded by leading biotechnology investors, including The Column GroupTopspin PartnersOrbiMed AdvisorsEcoR1 Capital, Fidelity Management & Research Company, Trinitas Capital, Foresite Capital, Taiho Ventures, Memorial Sloan Kettering, Kravis Investment Partners and NS Investment. ORIC is headquartered in South San Francisco, California.