Application Scientist

Inspiring advances in bioprocessing, Repligen is a leader in bioprocess filtration, pre-packed chromatography and Protein A ligands development. Propelled by a culture of innovation and collaboration, and with a focus on cost and process efficiencies, our people and our technologies help meet critical bioproduction demands worldwide.  Named one of the fastest growing biotech companies in the USA, Repligen is headquartered in Waltham, Massachusetts with major manufacturing sites in Massachusetts, California, Sweden, and Germany.  

We are seeking an Application Scientist within the research and development group focusing on downstream technologies, specifically on OPUS packing development and process/ product improvements.

https://www.youtube.com/watch?v=F1DCSBs9eTk 

Responsibilities include:

• Develop and tech transfer chromatography column packing methods for various resin types and pre-packed column sizes into commercial production

• Application scientist lead within new product development and product improvement teams

• Generate, analyze and document data for application notes, publications and to verify new and existing product performance claims

• Provide technical support for on-going commercial manufacturing processes either in a troubleshooting or process improvement role

• Contribute to experimental design approaches within a multidisciplinary research and development team

• Clear and detailed documentation of work through maintenance of an electronic based scientific notebook, technical reports and oral presentations

• Actively review and report on relevant technology publications

Skills:

• Experience packing chromatography columns with a variety of resins, column hardware, and scales

• Purification of proteins using column chromatography

• Operation of chromatography process equipment such as AKTA lab and process scale systems

• A background in biochemistry or experience with biochemical assays is desired

• Previous experience with statistical Design of Experiment (DoE) methodologies and software

• Exceptional in independent analytical assessment, problem solving and decision making

• Familiarity with GMP, GLP and ISO 9000/2001 quality systems is a plus

Qualifications:

• A minimum of a BS degree in Chemistry, Biochemistry, Biology, or Chemical Engineering would have the requisite theoretical background

• A minimum of 2-5 years experience in the biotechnology manufacturing and/or process development with focus in chromatography technologies

• Experienced in column chromatography and column packing

• Skilled in analytical assessment and problem solving

• Proven ability to engender cooperation at all levels across functional departments.

• Attention to detail, excellent verbal and written communication skills, and strong organizational skills

We are an Equal Opportunity Employer.