R&D Associate (Formulation Development)

Location
Tarrytown, NY, United States
Posted
May 29, 2019
Ref
16427BR
Required Education
Associate Degree
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary
We are seeking a R&D Associate within the Formulation Development Group of Regeneron Pharmaceutical Inc. at Tarrytown, NY. The R&D Associate will be responsible for formulation and manufacturing process development at all stages of product development and commercialization for different drug product modalities. In addition, the R&D Associate will carry out research on protein formulation, stability and characterization, and develop new formulation and drug delivery technologies.

Responsibilities

• Leads and participates in formulation and product development and stability assessment activities that may include candidate screening and selection, developing lyophilized or liquid formulations for all phases of pre-clinical, clinical and commercial development.

• Establishes a comprehensive physicochemical knowledge base of therapeutic drug candidates and utilizes it to identify critical quality attributes for formulation and drug product development, and to support various cross-functional processes.

• Develops fit-for-purpose analytical methods to support biophysical characterization, formulation and process development and research stability testing.

• Independently designs, executes and documents robust stability studies and other experiments to support stability testing therapeutic protein molecules.

• Utilizes statistical science knowledge for study design and data analysis.

• Presents work at group, department and cross functional meetings.

• Participates in research and technology innovation projects.
Requirements

• M.S. or B.S. in Pharmaceutical Sciences, Biochemistry, Biophysics, Chemistry, Chemical Engineering, or a related discipline with 2-3 years of relevant industry working experience.

• Strong technical knowledge base and experience with protein/peptide chemistry, biophysical/biochemical characterization of proteins, bioanalytical method development and biomolecule product development is preferred.

• Hands-on experience and trouble-shooting proficiency with applying chromatographic (HPLC, UPLC, column chromatography), visible and subvisible particle analysis, capillary electrophoresis and/or biophysical techniques (UV-vis, DLS, CD, FTIR, DSC, AUC, Fluorescence, Raman spectroscopy) for protein characterization are highly desirable.

• Expertise or familiarity with SAS JMP or similar statistical packages for data fitting and modeling is highly preferred.

• Excellent oral and written communication skills.

• Demonstrated track record of peer-reviewed publications is preferred.

• Enthusiasm in science with a motivation for making contributions in a team environment is necessary.

• Ability to quickly adapt to changes in project direction.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.