Research Associate, Molecular Biology & Engineering (24)

Employer: Bristol Myers Squibb Company
Location: Redwood City, CA, United States
Start date: May 23, 2019

Discipline: Science/R&D, Research, Molecular Biology
Required Education: Bachelors Degree
Position Type: Full time
Hotbed: Biotech Bay, Best Places to Work

Job Details
Company

Job Details

Summary

We are looking for a motivated and energetic candidate to join the Transgenic Discovery team in Redwood City. This is a highly collaborative environment focused on the discovery of life-saving, biologics-based medicines. The candidate will be responsible for bridging in vivo mouse work with in vitro phenotyping and characterization of genetically modified mice in support of our antibody discovery platform and therapeutic program advancement. The position will also play a prominent role in cell line engineering projects in the antibody and therapeutic areas.

Responsibilities

Responsible for designing and troubleshooting new genotyping assays, tracking, and managing all genotyping performed off-site.
Execute screening for new genetically modified mice and cell line development.
Perform genotyping, report and present data to support the validation of new genotyping assays.
Work interactively with drug discovery teams on-site to validate, characterize, and distribute mouse models that directly address drug discovery and program validation.
Compile data supporting phenotypic characterization and evaluation of transgenic mouse portfolio.
Collaborate on cell line development projects through engineering, screening, and validation of isogenic cell lines and in pooled screening applications.
Independence in experiment design, execution, troubleshooting, data interpretation and literature search is required.

Requirements

A B.S. with a minimum of 5 years of experience, or an M.S. with a minimum of 1+ years of experience with a strong scientific knowledge and research experience in immunology/molecular biology is preferred.
Must be well versed in mouse genetics, mouse breeding, and genotyping
Strong molecular biology skills including experience in genotyping methods (PCR, RT-PCR, CNV assays, DNA gel analysis) are required.
Working knowledge of in vitro gene expression (RT-PCR, qPCR, ddPCR or similar) and immunology assays (immunizations, ELISAs, FACS, Western blotting, SPR or similar).
Knowledge of cell engineering technologies, siRNA/shRNA knockdown, CRISPR-mediated genome editing.
Experience with multicolor flow cytometry and cell sorting including design, execution and analysis is strongly preferred.
Competency in data organization, e-notebook and database usage are a must.
Proficiency in scientific computer programs including Microsoft Excel, GraphPad Prism, Spotfire, FlowJo.
Position requires ability to work independently and collaboratively across a dynamic scientific environment, therefore excellent communication skills, both written and verbal, and strong interpersonal skills are necessary.

Company

Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

At Bristol Myers Squibb, we believe in the power of science to address some of the most challenging diseases of our time. Our focus on these unmet needs comes during a remarkable time, when unprecedented scientific breakthroughs are advancing the treatment of disease as never before in human history.

We work every day to transform patients’ lives through science. Each day, our employees around the world work together for patients – they are at the center of everything we do. They inspire us. They are the reason we come to work each day.

We combine the agility of a biotech with the reach and resources of an established pharmaceutical company to create a global leading biopharma company powered by talented individuals who drive scientific innovation.

Company info

Website: http://www.bms.com/
Phone: +1-800-332-2056
Location: 430 E. 29th St
14th Floor
New York
New York
10016
United States

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