DMPK Senior Research Associate to Scientist I

Senior Research Associate to Scientist I, DMPK

Description:

The primary responsibility of the position is to design and conduct in vitro ADME assays (e.g., CYP inhibition, metabolic stability and protein binding) and perform in vivo pharmacokinetic sample bioanalysis to support drug discovery and development. The incumbent will work closely with project teams to perform investigative DMPK studies to guide optimization of ADME properties and selection of potential drug candidates.

Qualifications and Experience:

• BS, MS or PhD degree in biochemistry, analytical or organic chemistry, or other relevant fields
• For candidates with a BS or MS degree, a minimum of 3 years of experience with in vitro DMPK assays in the drug discovery or drug development environment; for candidates with a PhD, no industry experience is required
• Hands-on experience with in vitro ADME assays including CYP inhibition, metabolic stability and protein binding is required; experience with metabolite identification is desired
• Hands-on experience with LC/MS/MS (e.g., Sciex triple quadrupole or Thermo Q-Exactive) is required
• Ability to troubleshoot and optimize assays as needed
• Excellent communication skills (especially written) are required

As an equal opportunity employer, ChemoCentryx, Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@chemocentryx.com for assistance.

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To all recruitment agencies: ChemoCentryx, Inc. does not accept unsolicited agency resumes and will not be responsible for the payment of placement fees related to unsolicited resumes submitted to open positions, job aliases, or to our employees.