Temporary Research Associate(BS/MS)

Ionis Pharmaceuticals, Inc., located in the North San Diego County city of Carlsbad, was founded in 1989 and was purposely designed to create a better, more efficient drug discovery platform, establish a new innovation-centered business model, and maximize the value of every medicine created and get it to the people who need it most as quickly and as efficiently as possible.

With the RNA molecule as the basis of our novel drug discovery platform, we are targeting an unprecedented range of therapeutic areas. Our antisense therapies are disrupting diseases and changing their course—from the rarest of conditions, to those that impact millions of people. We currently have three commercial products and more than 40 potentially transformative medicines in our pipeline designed to treat a broad range of diseases.

Ionis is a challenging, motivating and rewarding environment designed to foster innovation and scientific excellence. Our success is a direct result of our outstanding employees. We are interested in bringing together individuals with different skill sets into this creative environment to be part of a productive team. Join us and experience our unique culture while you develop and expand your career.

Temporary Research Associate (BS/MS)

 The Antisense Drug Discovery department seeks a Research Associate (BS/MS) to temporarily join the lead identification team. In this position, the successful candidate will assist in the evaluation of the effect of antisense oligonucleotides on the expression of specific transcripts, characterize lead inhibitors as well as examine the cellular mechanisms that contribute to oligonucleotide activity in mammalian cells. Primary responsibilities include mammalian cell culture, oligonucleotide transfection, RNA isolation and quantitative RT-PCR. We are looking for motivated individuals with strong attention to detail, experience in cellular and molecular biology and strong computer skills. The initial contract term is four months.

RESPONSIBILITIES:

• Mammalian cell culture (primary and immortalized)
• Antisense oligonucleotide transfection/screening
• RNA isolation and quantitative RT-PCR
• Operation of automation
• Analysis and presentation of data/results
• Performs experiments with minimal guidance and prepares summary of results for review and interpretation

REQUIREMENTS:

• B.S. with 1-5 years of experience or M.S. with 0-3 years of experience in Biology or a related field
• Extensive experience in mammalian cell culture is required
• Demonstrated experience with basic laboratory skills such as lab math calculations, solution/media preparation and dilutions is required
• Demonstrated experience with PCR, RT-PCR and qPCR is required
• Proven ability to analyze experimental data and effectively explain results
• Excellent written and verbal communication skills
• The ability to be flexible as workload and priorities demand
• The ability to work successfully both independently and as part of a team
• An ability to be productive and successful in an intense, fast-paced work environment

Please visit our website, www.ionispharma.com, for more information about Ionis.

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.