Sr. Research Associate, Research Biology (In Vivo)

Location
San Francisco, CA, United States
Posted
May 20, 2019
Ref
3486-360-R
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Position Overview

Nektar is seeking an experienced Sr. Research Associate to provide hands-on in vivo and ex vivo research support for early and developing programs targeting immuno-oncology and inflammatory diseases.

We are seeking someone who is highly proficient in in vivo drug administration by multiple routes and sample collection for ex vivo analysis for flow cytometry analysis. Expertise in in vivo tumor models is required, and experience in auto-immune/inflammatory disease models is a plus.

Responsibilities:
  • Conducts pharmacological evaluation of test agents (small molecule and biologics) in subcutaneous and orthotopic in vivo models of oncology.
  • Extensive experience in conducting in vivo tumor models, administering test articles (i.v., s.c. and p.o. required), and collecting samples. Will assist in or lead project teams in sample processing, homogenization, or generation of single-cell suspensions for ex vivo flow cytometry analysis.
  • Collects and records clinical measurements and observations. Candidate will be responsible for entering data from multiple studies in a timely manner and must be able to communicate experimental results within the department effectively.
  • Proficiency in in vitro cell culture, cell culture scale-up for implantation, cell banking and maintenance of frozen stocks utilizing aseptic technique is preferred.
  • Basic skills in flow cytometry techniques and data analysis are preferred.
  • Maintains familiarity with current disease relevant in vivo models for testing efficacy and pharmacodynamics of novel biologic and small molecules to support preclinical development and investigational new drug filings.
  • Contributes to preclinical research through validation or development of new models.
  • Experience in preparing basic formulations and dosing solutions is desired.
  • Exercises technical discretion in the design, execution and interpretation of experiments that contribute to project strategies.
  • Performs research and/or development independently or in collaboration with others.
  • Maintains a high level of professional expertise through familiarity with scientific literature.
  • Ensures compliance with good laboratory practices and other regulatory guidelines.
  • Understands and implements study protocol according to AAALAC and other guidelines.
Requirements:

A minimum of a Bachelors degree in a scientific discipline is required. Equivalent experience may be accepted. A minimum of 8 years work experience in a research and/or development environment is required. Additional Requirements Include: Ability to work collaboratively within a team as well as independently, provide and receive technical assistance to/from others in a wide range of laboratory-based activities/techniques, while displaying strong organizational and timely record-keeping skills. Ability and willingness to follow instructions to learn new techniques and improve on existing skills is required. Ability to multi-task and perform work with a high degree of attention to detail while supporting programs in a fast-paced environment. Requires occasional weekend hours. Must have excellent analytical skills, strong organizational skills, and significant hands-on laboratory experience. Excellent oral and written communication skills, with the ability to independently write reports is essential. Experience working in an FDA-regulated environment is highly desired.

We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.