Pharmacyclics, LLC

Senior Systems Engineer

Sunnyvale, CA
May 14, 2019
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Pharmacyclics is committed to the development and commercialization of novel therapies intended to improve the quality and duration of life and to resolve serious unmet medical needs for cancer patients. Pharmacyclics is a wholly-owned subsidiary of AbbVie (NYSE:ABBV), a global, research-based biopharmaceutical company. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products and a pipeline containing multiple promising new molecules that are being studied in more than 200 clinical trials for over 20 different types of cancer.

More than 1,200 Pharmacyclics and AbbVie research scientists, clinicians, marketing, operations and corporate professionals work in the San Francisco Bay Area. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. Together, we are striving to outsmart cancer.

General Position Summary/Purpose:

As a member of the Infrastructure Engineering group, the Senior Systems Engineer will be responsible for building and maintaining enterprise Linux and Windows Server systems and Oracle and SQL databases within a highly virtualized hybrid cloud environment. Ideal candidates will have a strong ability to script and code with an understanding of automation, orchestration, and infrastructure as code. The candidate should be a proactive leader with strong analytical and assessment skills who strives for excellence in everything that they do.

Key Accountabilities / Core Job Responsibilities:

  • Provide senior level engineering leadership for system and database deployment in a hybrid cloud environment
  • Be key subject matter expert for Linux and Windows systems and Oracle and SQL databases
  • Maintain and ensure the reliability and performance of all enterprise systems
  • Plan, develop, and deliver system and data driven projects on time and on budget
  • Provide T3 support for business critical incidents escalated from our T2 operations team
  • Install, test, configure, harden, and optimize computer hardware and software systems
  • Build, optimize, and manage on premise infrastructure to support business needs
  • Build and maintain Linux and Windows Server systems
  • Build and maintain Oracle and SQL databases
  • Manage Active Directory roles and features including group policy and Azure AD
  • Build and maintain servers and interconnected systems within VMware, AWS, and Azure
  • Lead effort for automation and orchestration for infrastructure systems and servers
  • Implement and maintain tools to support infrastructure and application activities
  • Support audit and compliance processes (internal and external)
  • Troubleshoot issues to find root cause and participate in corrective action/preventive action measures to remediate issues
  • Coordinate requirement gathering with internal business customers and interface throughout development process
  • Work with cross functional IT teams on various projects
  • Manage and maintain infrastructure software and tools
  • Work closely with 3 rd party partners and vendors
  • Remain current with the latest technologies and solutions
  • Drive continual improvement
  • Other duties as assigned

Required Expertise

  • Deep understanding of Windows and Linux Operating Systems
  • Deep understanding of SQL and Oracle Databases
  • Deep understanding of Hybrid Cloud environments and integrations with AWS and Azure
  • Proven experience integrating and building systems and databases in an enterprise environment
  • Experience in automation, orchestration, and building reliable, scalable infrastructure as code
  • Solid Troubleshooting, diagnosing, and problem solving skills to solve issues within GxP production environment
  • Deep knowledge of Active Directory, authorization, and authentication.
  • Solid understanding of how systems integrate with other infrastructure components (Compute, Storage, HPC, etc.)
  • Solid understanding of ITIL processes including incident management, change management and problem management
  • Solid planning and execution skills and ability to deliver projects on time and on budget
  • Ability develop technical documentation for projects including changes to systems
  • Great communication skills, able to interface and communicate with the business on how system technology integrates and works
  • Can work autonomously, is a team player and possess the ability to interact and interface with all levels of management.
  • Expertise with:
    • Microsoft Windows Server OS: Server 2008 R2, Server 2012 R2, Server 2016
    • Linux OS: RHEL 6 & 7, CentOS, Debian etc.
    • VCenter Server Management 6.x and ESXI 6.x
    • Database Management - OrcaleDB, MySQL, SQLite, AWS Database etc.
    • Cloud: Implementing systems in AWS & Azure (EC2, S3, Route53, Lambda VPC, Azure VM, EBS, Blob etc.)
    • Active Directory and administration and maintenance and Azure AD (ADUC, ADCS, File Services, IIS, SSCM, DNS, DHCP, RDS, Group Policy etc).
    • Scripting knowledge (any mix of): Powershell, VB, WMI, ASDI, Bash, Perl, Python etc.
    • Configuration Management: SSH, Github, Jira, Ansible, other configuration management tools


  • 10+ years of Information Technology (IT) experience supporting enterprise class systems and databases within a hybrid cloud environment
  • Bachelor's Degree in Computer Science or relevant work experience
  • Certified professional in one or more of the following:
    • Microsoft Certified Solution Associate (MCSA)
    • Microsoft Certified Solution Expert (MCSE)
    • Red Hat Certified System Administrator (RHCSA)
    • Red Hat Certified Engineer (RHCE)
    • AWS Certified Tracks

Equal Opportunity Employer Minorities/Women/Veterans/Disabled