Research Associate- TCR Discovery

Research Associate, TCR Discovery

Position Overview

As a Research Associate you will be working with the TCR Discovery team developing new assays that will fuel the discovery of clinically useful biomarkers and therapeutic candidates. You will implement a variety of cellular assays aimed at identification of T and B cell subsets. You will also play a key role in the design and implementation of read-outs for T cell antigen-specificity and effector function, with minimal supervision. You will also be accountable for coordinating general lab maintenance tasks such as ordering reagents, restocking lab consumables, and regular upkeep of lab equipment.

Responsibilities

• Implement complex cellular assays (isolating and culturing PBMC subsets, flow cytometry/cell sorting, T cell phenotyping and cell stimulation, etc.)
• Culture and maintain cell lines for cell-based assays 
• Manage cell stock inventory
• Coordinate day-to-day lab activities including equipment maintenance, reagent orders, restocking consumables, etc.
• Effectively work and communicate with group members and other groups in a dynamic and fast paced environment in order to accomplish goals
• Perform thorough documentation of lab activities, data analysis and regular presentations of work in progress to the group

Requirements 

• Bachelor degree in biological sciences
• 2+ years lab experience in immunology or related field 
• Experience with cell culture and aseptic technique is required 
• Experience with multiparametric flow cytometry is required 
• Experience with handling human tissue specimens (blood, etc.) is a requirement 
• Exceptional organizational skills and attention to detail 
• Proficiency with cell transfection and viral vector-based cell infection is a plus 
• Experience with cell sorting is a plus 
• Familiarity with BSL-2 protocols and best-practices is a plus 
• Experience training and managing lab members and overseeing projects is a plus

About the TCR Discovery Team: Based in South San Francisco, Adaptive’s Discovery team is developing a world-class high-throughput TCR discovery platform. Our mission is to resolve the T cell repertoire by combining Adaptive’s core next generation TCR sequencing with cellular immunology assays to identify antigen-specific TCRs at an unprecedented scale. Our goal is to produce clinically useful TCR-based biomarkers and therapeutics, and ultimately to map the universe of antigens recognized by human T cells. #BeingAdaptive

Adaptive Biotechnologies is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.  Equal Opportunity Employer/Veterans/Disabled