Skip to main content

This job has expired

You will need to login before you can apply for a job.

Research Associate I/II

Employer
Theravance Biopharma
Location
South San Francisco, CA
Start date
Apr 23, 2019

View more

Job Details

Position Summary

The department of Biology and Pharmacology is currently seeking a motivated Research Assistant/Associate to participate in drug discovery research. The successful candidate will work collaboratively with senior scientists to develop and execute pharmacodynamic and disease mechanism models designed to assess the pharmacological activity of novel molecules.  The successful candidate should have the ability and willingness to work in a variety of therapeutic areas. 

Duties and Responsibilities 

Research Associate should have strong in vitro / in vivo skills.  Ability to provide scientific inputs for new assay/ experimental model development. 

  • Data collection, evaluation and documentation
  • Rodent handling, dosing, and dissections
  • Basic rodent surgeries
  • Surgical/Assay preparation
  • Assay monitoring
  • Compound formulation, dilutions, dose calculations
  • Use of MS Excel, Word, and Graphpad® Prism software
  • Presentation of experimental findings to colleagues

 Qualifications

  • BS/MS in a relevant scientific discipline, and at least one year of drug discovery experience in a biotechnology/pharmaceutical or academic setting
  • Sound understanding of animal physiology and anatomy
  • Excellent organizational, written and oral communication skills
  • Experience in handling, dosing and induction of anesthesia in small animals
  • Knowledge in vitro assays, multicolor flow cytometry, ELISA, qPCR, MSD-based assays, and AlphaLISA is a plus
  • Ability to work efficiently and independently under minimal supervision in a dynamic team environment

Physical Requirements 

The incumbent may be required to sit, stand and walk for extended periods of time.  The incumbent may be required to climb, bend, lift, carry and kneel.  The incumbent will also spend a some time looking at the computer monitors and using his/her hands to operate office equipment.

Company

Theravance Biopharma is a diversified biopharmaceutical company with the core purpose of creating medicines that help improve the lives of patients suffering from serious illness.

Our pipeline of internally discovered product candidates includes potential best-in-class medicines to address the unmet needs of patients being treated for serious conditions primarily in the acute care setting. VIBATIV® (telavancin), our first commercial product, is a once-daily dual-mechanism antibiotic approved in the U.S., Europe and certain other countries for certain difficult-to-treat infections. Revefenacin (TD-4208) is a long-acting muscarinic antagonist (LAMA) being developed as a potential once-daily, nebulized treatment for chronic obstructive pulmonary disease (COPD). Our neprilysin (NEP) inhibitor program is designed to develop selective NEP inhibitors for the treatment of a range of major cardiovascular and renal diseases, including acute and chronic heart failure, hypertension and chronic kidney diseases such as diabetic nephropathy. Our research efforts are focused in the areas of inflammation and immunology, with the goal of designing medicines that provide targeted drug delivery to tissues in the lung and gastrointestinal tract in order to maximize patient benefit and minimize risk. The first program to emerge from this research is designed to develop intestinally restricted pan-Janus kinase (JAK) inhibitors for the treatment of a range of inflammatory intestinal diseases.

In addition, we have an economic interest in future payments that may be made by Glaxo Group Limited or one of its affiliates pursuant to its agreements with Innoviva, Inc. relating to certain drug development programs, including the combination of fluticasone furoate, umeclidinium, and vilanterol (the Closed Triple), currently in development for the treatment of COPD and asthma.

Company info
Website
Phone
650-808-6000
Location
901 Gateway Boulevard
South San Francisco
California
94080
US

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert