Senior Research Investigator I

Senior Research Investigator - In Vivo Pharmacology

We are seeking a Senior Research Investigator, In Vivo Pharmacology who will have scientific and managerial responsibility for a group of scientists conducting in vivo research in the field of autoimmune diseases. This individual will report to the Head of the Immunosciences In Vivo Pharmacology Group and will interact seamlessly with other scientists and functional groups within a drug discovery team to formulate and implement the in vivo strategy for the programs in the Immunoscience Portfolio. While the major focus of this position will be the in vivo evaluation of novel therapeutic agents that will support these drug discovery efforts, additional responsibilities include the identification and validation of novel disease and target specific biomarkers, and the development of new pharmacodynamic and disease models for autoimmune and immuno-oncology indications. Other responsibilities include but are not limited to: 1- Supervise technical staff with extensive scientific knowledge; 2- Prepare, review and deliver scientific presentations to internal and external stakeholders; 3- Interact with senior management and key opinion leaders.

Requirements

Ph.D. in Immunology or related field, with a minimum of 8 years' working experience, preferably within the Pharmaceutical/Biotechnology sector. Knowledge of the Immunology/Inflammation therapeutic area with a strong in vivo background is essential. Extensive understanding of PK/PD assessments in models of disease and experience in designing ex vivo studies to assess pharmacodynamic and target engagement endpoints, is also a must-have. Previous working experience with histology and immunohistochemistry is preferred. The position will require strong scientific and managerial skills and the successful candidate will have proven leadership ability, a strong collaborative style, excellent communication skills, and a publication record in peer reviewed journals.