Research Associate I, Antibody Engineering & Technologies

South San Francisco, CA, United States
Apr 19, 2019
Science/R&D, Research
Biotech Bay
Required Education
Associate Degree
Position Type
Full time
Company Description

Five Prime Therapeutics, Inc. (NASDAQ: FPRX) is a publicly traded, clinical-stage biotechnology company focused on discovering and developing innovative immuno-oncology protein therapeutics to improve the lives of patients with serious diseases. We have an industry-leading and differentiated drug discovery platform. Our comprehensive proprietary libraries of the extracellular proteome, differentiated screening capabilities and protein therapeutic generation and engineering capabilities comprise a unique and powerful IND engine that will continue to generate important development programs. This uniquely positions us to discover novel pathways and targets in immuno-oncology. Our success with our drug discovery platform has led to a pipeline that is on track to more than double to five development programs in clinical trials across multiple indications in 2018. We also have several undisclosed research programs at different points of the target validation and molecule generation phases that have the potential to yield our next wave of development-stage therapeutic biologics. And we continue to fuel this process at the earliest stages with new screens planned this year.

Five Prime is committed to innovation and outstanding science to develop effective new drugs for the treatment of severe diseases. We value our culture of openness, collaboration and productivity. The company is in a strong financial position and has an effective executive team and Board of Directors. Discover more about FivePrime at

Job Description

The Position:

We are looking for a highly motivated Research Associate with molecular background to join the Antibody Engineering and Technologies Group within the Biotherapeutics Department. The successful candidate will be responsible for learning and implementing recombinant DNA approaches to support research team needs which include plasmid DNA production and QC, recombinant DNA cloning, Sanger sequence data analysis, and tracking the DNA preparations and constructs in databases. The candidate must be self-motivated, detail oriented and thorough, and be capable of working both independently and in a team environment.


Education and Experience:
  • B.S. in Molecular or Cell Biology is required
  • 0-4 years of academic/industry experience
  • The successful candidate must have experience in basic molecular biology and recombinant DNA technologies

  • Experience in recombinant DNA technologies including cloning, assembly, transformations and DNA preparation required
  • Exposure to PCR techniques and Sanger sequence data analysis
  • Some experience with the use of robotics systems such as QPix and Tecan
  • Background in bioinformatics and experience with NGS is a plus
  • Meticulous and accurate record keeping
  • Experience in mammalian cell culture techniques is a plus
  • Excellent organizational and communication skills are required
  • Ability to work in a fast paced team environment is also necessary

Additional Information

At FivePrime, we believe a diverse workforce drives our success as a company. We are always working to create an environment where different backgrounds and viewpoints are valued and celebrated.

FivePrime is an equal opportunity employer. FivePrime makes employment decisions, including in recruitment and selection, without consideration of race, color, national origin, religion, sex, gender, gender identity or expression, sexual orientation, age, veteran status or disability.Please call or reply with any comments.

All your information will be kept confidential according to EEO guidelines.