Scientist, Genomic Technologies

Employer
AbbVie
Location
North Chicago, IL, US
Posted
Apr 18, 2019
Ref
1902862
Required Education
Masters Degree/MBA
Position Type
Full time
The GRC Genomic Technologies Team supports AbbVie preclinical and clinical research teams by applying genomic profiling technologies with the goal of improving the success rates for drug discovery and development. We apply genomic profiling technologies to identify and validate targets and biomarkers, improve understanding of preclinical models and candidate drug molecules, select patients and understand patient responses in AbbVie clinical trials. The successful candidate will be responsible for carrying out genomic profiling experiments and communicating results to stakeholders and collaborators and will also help drive efforts to expand genomic profiling capabilities to serve unmet needs.

Responsibilities:
  • Work with AbbVie Genomic Research Center (GRC) stakeholders and AbbVie therapeutic area (TA) scientists to meet the genomic profiling needs from active studies. Collaborate on experiment design, execution, and analysis to deliver high quality results under agreed upon timelines.
  • Process and perform QC analysis of samples from tissues and cells. Perform initial data QC and first pass analysis of results. Partner with bioinformatics specialists and disease area scientists to interpret results and design follow up experiments.
  • Operate and maintain genomic technology platforms within centralized technology group.
  • Effectively communicate with stakeholders, especially around trouble-shooting and responding to changes in priorities and adjusting timelines.
  • Prepare written summaries of experimental results and verbally present at team meetings.
  • Keep current on rapidly evolving genomic technology platforms, especially DNA microarrays, RNAseq, DNAseq, and digital PCR. Contribute to technology development efforts as needs arise.


Level and compensation will be commensurate with experience.

Basic:
  • MS in molecular biology, genomic sciences or a related field with 5+ years of experience, or BS with 8+ years of experience.
  • Demonstrated record of hands-on experience and deep technical knowledge of genomic profiling technologies with emphasis on next generation sequencing platforms (targeted DNAseq and RNAseq).
  • Experience being part of a centralized technology group is desirable. Industry experience is desired but willing to consider individuals with equivalent years of experience in academic or non-industry research settings.
  • Expert and detailed knowledge of genomic sample processing, sample QC, genomic profiling data QC and analytical methods.
  • Familiarity with LIMS, sample tracking, and workflow optimization.
  • High attention to detail, strong written and verbal communication skills, ability to work independently and as part of teams.
  • Ability to work in fast-paced, dynamic environment and to independently carry forward multiple projects in parallel.

Key Leadership Competencies
  • Builds strong relationships with peers and cross functionally with partners to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.
  • Strong interpersonal and communication skills with demonstrated ability to work within a team environment.