Associate Principal Scientist, Process Chemistry, MRL San Francisco
Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.
Merck is currently seeking a qualified synthetic organic chemist to join the Discovery Process Chemistry (DPC) group at our South San Francisco, CA site. The core responsibility of the successful candidate will be to drive the development of innovative solutions to complex chemistry problems across a diverse portfolio of projects in the discovery phase, from lead identification through candidate selection, with the goal to apply these solutions to facilitate medicinal chemistry research by overcoming synthetic bottlenecks, streamlining SAR analogue synthesis, and providing access to novel chemical space. The position is also responsible for defining scalable synthetic routes and successfully transitioning candidate compounds from discovery into early development, as well as managing supply of Active Pharmaceutical Ingredients (APIs) at varying scales during this period. Close collaboration with chemistry colleagues in Medicinal Chemistry and Process Chemistry, as well as a broad array of other discovery and preclinical research groups, will be expected. As such, subject matter expertise in Process or Medicinal Chemistry is critical. The candidate must be highly self-motivated, possess strong experimental skills, have excellent written and oral communication abilities, collaborate effectively on multidisciplinary teams, and be able to demonstrate flexibility in adapting to change in a fast-paced, dynamic research environment. A demonstrated ability to develop talent through good mentoring skills is an asset as the successful candidate will be expected to grow into the direct supervision of junior colleagues. In addition, the candidate will be expected to remain current with the latest synthetic methodologies, drive innovation, actively apply new concepts to continuously improve PR&D capabilities, and be active in the external scientific community via publications and external presentations.
Education Minimum Requirement: PhD in Organic Chemistry or related field. Required Experience and Skills:
- A minimum of 3 years experience with a proven track record of scientific excellence and successful research in process and/or medicinal chemistry
- Scientific reputation supported by peer-reviewed publications and external presentations
- Expertise in organic synthesis
- Demonstrated creativity and innovation in problem solving
- Productivity and efficiency working in the lab
- Strong written and oral communication skills
- Excellent collaboration skills
- Ability to contribute on cross-functional teams
Preferred Experience and Skills:
- Demonstrated mentorship of junior colleagues or associates is a plus
Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.
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Job: Research Science (59000450)
Other Locations: Rahway, NJ, US
Employee Status: Regular
Number of Openings: 1
Shift (if applicable): N/A
Hazardous Materials: Yes; Chemistry R&D