Senior/Executive, Medical Director, Clinical Development (MD)

Nurix Inc.
San Francisco, California, United States
Apr 06, 2019
Biotech Bay
Required Education
Position Type
Full time
We are seeking an experienced clinician with strong leadership skills who is driven by science and the desire to develop novel therapies for cancer patients. The successful candidate will have expertise in the design and conduct of early phase oncology clinical trials and a strong interest in translational medicine.
Reporting to the Chief Development Officer, the Medical Director will be responsible for the design, implementation, monitoring, data analysis and reporting of clinical studies for Nurix's oncology portfolio. As a member of the Development Leadership team, the successful candidate will play a key role in building and shaping the Development organization at Nurix. The Medical Director will also serve as a medical expert resource for drug discovery teams and business development activities. The role provides an opportunity for leadership growth in a dynamic small company environment.

Specific responsibilities include:
  • Provide strategic input for innovative clinical development plans, incorporating the current therapeutic area landscape
  • Lead the design and implementation of early stage clinical projects, with responsibility for medical aspects of phase 1-2 clinical trials
  • Serve as lead author of clinical documents: protocols, investigator's brochures, case report form design and data analysis plans
  • Lead preparation of clinical sections of relevant regulatory filings to Health Authorities
  • Partner closely with the Clinical Operations head in the conduct and execution of Nurix's clinical trials
  • Serve as Medical Monitor for clinical trials, reviewing safety and efficacy data for routine medical data review, trend review, and safety signals from ongoing trials
  • Support exploratory biomarker efforts to aid clinical and project data-driven decisions
  • Lead medical aspects of investigator and clinical advisory boards
  • Develop and manage relationships with key opinion leaders for clinical programs
  • Represent Nurix at external events, including scientific and medical conferences and business development activities

  • MD with board certification or eligibility in Oncology or Hematology/Oncology
  • Five to seven years of drug development experience in biotechnology or pharmaceutical industry, or a combination of academia and industry
  • Proven experience with clinical trial design, execution, medical monitoring, and reporting of controlled clinical trials in oncology including working with external service providers
  • Experience with design, execution, and analysis of Phase 1-2 clinical oncology studies with small molecule targeted or immunological therapies
  • Demonstrable knowledge of regulatory procedures and guidelines in the US and other geographic regions
  • Understanding of basic science relevant to clinical oncology
  • Ability to work collaboratively in a fast-paced matrix environment
  • Excellent written and oral communication skills