Research Associate II, Formulation Development

La Jolla/San Diego, California
Mar 26, 2019
Required Education
Bachelors Degree
Position Type
Full time

About Us:


Founded in 2013 and based in San Diego, Arcturus Therapeutics Ltd. is a publicly traded RNA medicines company. Arcturus’s commitment to the development of novel RNA therapeutics has led to partnerships with Janssen Pharmaceuticals, Inc., part of the Janssen Pharmaceutical Companies of Johnson & Johnson, Ultragenyx Pharmaceutical, Inc., Takeda Pharmaceutical Company Limited, Synthetic Genomics Inc., and Cystic Fibrosis Foundation Therapeutics Inc.


Our corporate culture is diverse, open and creative. We value collaboration and teamwork. We are looking for team members to grow with us and with a strong dedication to the highest levels of scientific excellence.


Position Details:


The Research Associate II, Formulation Development will be responsible for designing, directing, planning, coordinating and troubleshooting all aspects of lipid nanoparticle-based formulation development. Our ideal candidate is hands-on, bringing expertise within nanoparticle formulations, and be able/willing to lead and mentor a small team of scientists and research associates.


You Will:


Serve as a subject matter expert on the team in the area of lipid nanoparticle-based drug delivery systems for nucleic acids; Design and direct development of novel lipid nanoparticle formulations for delivering nucleic acids to various cell and tissue types; Design, direct and manage studies aimed at a screening of formulations including but not limited to a physico-chemical screen, stability studies and bio-evaluation; Actively contribute to the development of analytical methods for thorough characterization of lipid nanoparticle formulations; Represent formulation development function in various project team meetings and contribute to overall project goals and deliverables; Demonstrate scientific excellence through filing patents and publishing scientific articles in peer-reviewed journals; Contribute to formulations development sections of regulatory filings (IND, NDA etc.) Represent company at scientific conferences and meetings; Perform other duties as necessary. About You:


Ph.D. in Chemistry or pharmaceutical sciences with more than 8 years of direct experience in design and development of lipid nanoparticle-based drug delivery systems for nucleic acids required; Deep understanding of all aspects of formulation development and characterization including physico-chemical, stability and biological evaluation required; Excellent scientific publication and patent record in the field of lipid nanoparticle-based drug delivery systems required; Thorough knowledge and understanding of PK/PD and mechanistic aspects of uptake of lipid nanoparticle-based formulations required; Excellent oral and written communication skills required. Must be an independent thinker with a passion for developing innovative formulation technologies; Experience in writing formulation development section of regulatory filings (IND, NDA etc.) is desired. Arcturus is committed to equal opportunity and complies with all applicable national, state and local laws governing nondiscrimination in employment.




For more information about our company, visit




Job Type: Full-time