Pharmacyclics, LLC

DMPK (DM Focus) Intern

Sunnyvale, CA, United States
Mar 25, 2019
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Pharmacyclics is committed to the development and commercialization of novel therapies intended to improve the quality and duration of life and to resolve serious unmet medical needs for cancer patients. Pharmacyclics is a wholly-owned subsidiary of AbbVie (NYSE:ABBV), a global, research-based biopharmaceutical company. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products and a pipeline containing multiple promising new molecules that are being studied in more than 200 clinical trials for over 20 different types of cancer.

More than 1,200 Pharmacyclics and AbbVie research scientists, clinicians, marketing, operations and corporate professionals work in the San Francisco Bay Area. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. Together, we are striving to outsmart cancer.

Value to the Intern:

  • Learn to operate the Mass spectrometer
  • Learn the principles of Drug Metabolism and Drug-drug interaction (CYP Induction)
  • Learn how to use and conduct chemical structure analysis, using the ChemDraw software
  • Exposure to these skill sets and introduction to "Ways we Work" will be an excellent tool for the intern as they explore a future career, hopefully in the pharmaceutical industry.

Value to Pharmacyclics:

  • Conduct in vitro sample preparation and analysis for discovery compounds, as well as help in day to day activities in the laboratory. This will provide an additional pair of hands in the laboratory, help to increase throughput (screen more compounds) and turnaround time.
  • Student pool will bring diverse ideas into the Pharmacyclics work place.
  • At the end of the internship, intern will serve as a goodwill "Ambassador" for Pharmacyclics.

Job Requirements

  • Hands on experience in basic laboratory procedures, with the ability to learn and operate a luminometer, fluorimeter, qPCR instrument and softwares associated with these instruments
  • Good documentation skills - write procedures and enter data into laboratory or electronic notebook
  • Ability to quickly learn and understand new laboratory procedures; excellent interpersonal and communication skills

Education Requirements:

  • Prefer candidate that has biology/biochemistry/chemistry knowledge and is a science major
  • Candidate is a current college student (entering sophomore year or higher) or recent college graduate who is studying/has studied coursework in biology, biochemistry or related areas
  • Be an active student in good standing at a US accredited university
  • Maintain a minimum cumulative GPA of 3.0/4.0 or equivalent

Final Presentation

Each Intern is expected to prepare a short presentation to their team to share what they have learned through their internship, and how the knowledge acquired will help them in their future career. Presentations should be 10-15 minutes long and should include visual aid (posters or PowerPoint).

Equal Opportunity Employer Minorities/Women/Veterans/Disabled