Amgen

Pilot Plant - Senior Associate (Downstream)

Employer
Amgen
Location
Thousand Oaks, CA, US
Posted
Mar 22, 2019
Ref
R-70560
Required Education
Bachelors Degree
Position Type
Full time
We are seeking a Senior Associate for the Pilot Plant (based in Thousand Oak, CA) working in

the Downstream team. This position will execute a variety of production-related operations in a

large-scale facility, including but not limited to: performing processing on the floor (purification

of Drug Substance); performing supporting activities such as buffer preparation, and equipment

set-up/cleaning, and execution of downstream operations. Work will also include executing

production runs, experiments, commercial program support, and characterization efforts. A

significant amount of time will be spent performing 'hands-on' work in the plant. Additional

activities will include defining & documenting operation practices, ensuring documentation

accurately reflects operations performed, developing and implementing area improvements

(efficiency and safety) applying lean principles, commissioning equipment, and participating in

operations meetings.

The Thousand Oaks Pilot Plant performs frequent piloting of novel process operations (focusing

primarily on large molecule cell culture and purification operations), driving technology

development, supporting innovation across Amgen's entire spectrum, as well as executing non-

GMP and pre-pivotal GMP bioprocessing operations for multiple mammalian and microbial

Products, to develop & demonstrate production processes and produce bulk material. We produce sound, relevant data for the processes Amgen developments at meaningful scales that

enable the rapid, successful transfer of our output to more dedicated manufacturing spaces. The

environment is challenging, fast-paced and ever changing with varying degrees of process

definition, but very rewarding for those that like hands-on science and want to make process

improvements in a development space. Must be able to work off hours or non-standard shifts.

Basic Qualifications

Master's Degree

OR

Bachelor's Degree & 2 years of Manufacturing, Scientific or Operations experience

OR

Associate's degree & 6 years of Manufacturing, Scientific or Operations experience

OR

High school diploma/GED & 8 years of Manufacturing, Scientific or Operations experience

Preferred Qualifications
  • Bachelor's degree in Biology, Chemistry, Biochemical/Chemical Engineering, or other relevant field
  • 3+ years of experience in process development, biotechnology manufacturing, or Life Sciences or Engineering fields
  • Solid knowledge of upstream/downstream operations
  • General knowledge of the associated analytical and media/buffer preparation techniques
  • Energetic and technically-minded individuals, with strong interpersonal, leadership, and organizational skills
  • Demonstrated ability to learn new systems and applications, and various downstream techniques
  • Demonstrated ability to work effectively in team and/or project environments