Grad Intern - R&D (PKDM Transporter)

Cambridge, MA
Mar 22, 2019
Required Education
Bachelors Degree
Position Type
Full time
Amgen's 10-12 week internship program offers meaningful project experiences that impact patient's lives. This internship provides a great opportunity for a qualified individual who may want to obtain experience in industry during their graduate training. In addition, interns get exposed to executive and social networking events and to participate in community volunteer projects while growing scientifically. This internship also provides competitive compensation.

Relocation in the form of a miscellaneous allowance will be provided for eligible candidates.

The intern will focus on commercially available physiologically relevant 3D liver model systems to evaluate their application in improving in vitro to in vivo correlation (IVIVC) for small molecules pharmacokinetics, when transporters play an important role in the their elimination and disposition. The work will provide insight into our understanding of the value and limitations of available 3D liver models to potentially improve IVIVC in situations where metabolism and transporters work in concert to determine drug clearance . Additionally, the intern will have the opportunity to learn a variety of in vitro tools used to study drug interaction with transporters to support drug discovery and development. Depending on the progress made during this project, this work may lead to a peer reviewed publication.

Basic Qualifications

Amgen requires that all individuals applying for a grad internship or a co-op assignment at Amgen must meet the following criteria:

18 years or older

Graduated with a Bachelor's degree from an accredited college or university with a 3.0 minimum GPA or equivalent

Completion as a first year graduate student before internship starts and currently enrolled in a PhD for a PhD internship from an accredited college or university

Enrolled in an accredited college or university following the potential internship or co-op assignment

Must not be employed at the time the internship starts

Preferred Qualifications

Candidate pursuing a PhD degree in Pharmaceutical Sciences or related fields

Hands on experience with primary hepatocytes culture, any relevant 2D and 3D liver models and/or in vitro transporter assays is desired but not necessary

Experience with LC-MS analysis a plus

Ability to critically think, independent lab work, strong attention to details

Excellent written and oral communication skills

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

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