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Laboratory Scientist - MHC Tetramer Production

Employer
MBL International
Location
Des Plaines, IL
Start date
Mar 19, 2019

Purpose of Work:

Responsible for performing procedures specific to the production of MHC tetramers and to ensure manufactured products supplied to the customer meet the highest quality standards.

Essential Job Functions and Duties:

  • Perform laboratory processes involved in manufacturing and/or QC of products and the preparation of reagents/media.
  • Utilization of Good Manufacturing Practices (cGMP) and Good Laboratory Practices (GLP).
  • Protein purification techniques utilizing HPLC, spectrophotometry, and SDS-PAGE.
  • Cellular analysis by cell staining and Flow Cytometry.
  • Conduct testing for shelf-life studies on product retention samples.
  • Perform incoming inspection of Raw Materials as required.
  • Complete all required paperwork and records in a clear and succinct fashion as required by the department manager.
  • Clean-up work area and dispose of biohazard or other waste materials appropriately. 
  • Ability to recognize anomalies in the production process, make adjustments, and inform management regarding areas of improvement.
  • Operate and maintain department related equipment.
  • Order and stock supplies as needed and conduct monthly inventory of supplies.
  • Familiar with the Quality Management System and quality policies.
  • Familiar with applicable regulatory requirements (cGMP). 
  • Working knowledge of safety program procedures.

Other Job Duties:

Performs other duties as required.

Minimum Qualifications of the Position:

Education:

Bachelor’s degree in life sciences, biology, chemistry, biochemistry or closely related field.

Experience:

Must have two years of experience in protein purification and analysis.  Prefer prior MHC tetramer preparation experience and/or experience in immunology and immuno-onclogy.   Experience in Flow Cytometry is required.   Experience in HPLC is desirable.

Knowledge, Skills, Abilities:

  • Good communication skills, both written and verbal.
  • Ability to speak and write English and communicate specific principles in English\
  • Ability to follow instructions, both written and verbal.
  • Strong organization skills.
  • Strong troubleshooting skills.
  • Good manual dexterity.
  • Ability to perform laboratory procedures without supervision.
  • Ability to operate laboratory equipment.
  • Good team player.
  • Ability to multi-task effectively.
  • Ability to follow routine manufacturing processes without mistake or alterations.
  • Must deliver on time results that are clearly written and can be articulated.

Type of Work Environment:

Manufacturing Laboratory.

 

 

 

 

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