Bristol-Myers Squibb Company

Senior Research Investigator (Drug Discovery)

Cambridge, MA, United States
Feb 25, 2019
Required Education
Position Type
Full time
Senior Research Investigator (Drug Discovery)

Job Description

This Senior Research Investigator Drug Discovery will join the Cancer Resistance Biology Research Team at Bristol-Myers Squibb in Cambridge, MA to support preclinical drug discovery and development against therapeutic targets at the intersection of intrinsic tumor genetics and the extrinsic tumor microenvironment.

The qualified candidate is a highly motivated, interactive, and creative individual who possesses substantial experience in studying tumor biology and genetics, and experience or strong interest as to how these features impact immune responses to the tumor. Since BMS is a matrixed organization, the candidate will be expected to effectively collaborate with colleagues in supportive line functions (including oncology, immuno-oncology and immunology, medicinal chemistry, candidate optimization and translational medicine) to advance preclinical development of therapeutic candidates to early clinical development. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams, senior management and at external scientific meetings. The candidate will develop external partnerships/collaborations to advance internal programs, as appropriate. S/he will also manage a small in vitro biology lab to support their project responsibilities as well as to contribute to team held objectives, including new project and target ideas. This position is located in Cambridge, MA. There will be less than 10-20% travel.


  • A Ph.D. degree with a minimum of 4+ of relevant experience in cancer biology and genetics, immnuo-oncology or a closely related field
  • Industry experience with demonstrated abilities to drive preclinical development from target ID to clinical candidate selection, especially experience in small molecule drug discovery.
  • Demonstrated expertise to independently apply bioinformatics and data mining through multi-variate analysis; ability to effectively interact with core bioinformatics colleagues, as well as to use desktop tools/interfaces (e.g., Oncoland, Wuxi) and public databases (CBIO, Achilles, etc.)
  • Excellent oral and written communication skills, as is the ability to effectively present scientific data and concepts to international standards.

  • Experience or the ability to innovate in novel preclinical in vitro , in vivo and ex vivo oncology model development that enables bridging from tumor biology to host immunity is highly desired.
  • Management/supervisory experience


2-3 Research Scientists/Associates