Bristol-Myers Squibb Company

Senior Research Investigator (Genomics)

Location
Cambridge, MA, United States
Posted
Feb 25, 2019
Ref
R1508144_EN
Required Education
Doctorate/PHD/MD
Position Type
Full time
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

We seek a highly motivated, detail-oriented leader with broad experience in application of genomics tools in answering biological questions, specifically Next Generation Sequencing (NGS) work flows and associated analysis to be a strong contributor to the core Genomics Group that works with research investigators across many groups. The position will be part of an integrated team dedicated to understanding the mechanisms of Cancer resistance among other things. Primary responsibilities include various genomic and transcriptomic assay development and implementation in support of programs across multiple therapeutic areas, new genomic method development and optimization, establishing collaboration across genomics ecosystem in Cambridge.

Responsibilities:
  • Primary responsibilities will be genomics support for various programs.
  • Play a role in optimizing and developing new protocols or adopt and optimize existing protocols to suit needs.
  • Play a key role in the method development for novel High throughput single cell RNA and DNA sequencing.
  • The self-motivated candidate works independently and coordinates with various teams in a matrix environment.
  • Manage Research scientists to deliver data to investigators
  • Maintains lab notebooks, compiles data, and details written experimental instructions, particularly in areas involving new technology and/or novel experimental approaches.


Requirements:
  • The successful candidate will have Ph.D. in Molecular/Cell Biology or Genetics or Biochemistry with at least 5 years or M.S in Molecular/Cell Biology or Genetics with at least 8 years of relevant scientific lab experience with emphasis on Next Generation Sequencing (NGS) and other genomics methods and work flow.
  • Robust experience in NGS library generation and relevant method development.
  • Broad experience in advanced Cell and Molecular Biology technique is essential.
  • Experience in working with FFPE and other clinical sample handling preferred.
  • Detail oriented and effective communicator.
  • Expertise in Cell separation technologies such as FACS/Microfluidics a plus but not essential.
  • Strong focus, motivation, and commitment to hands-on lab work.
  • Ability to trouble shoot and make independent decisions regarding experimental details
  • Extensive people and project/matrix team experience, with demonstrated ability to work effectively within multidisciplinary teams.
  • Flexibility to accommodate to rapidly changing priorities and deadlines