Biologist - Cancer Cell Biology

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Responsibilities
Are you looking for a career in discovery research working for an extraordinary company? Are you passionate about your work and desire to contribute to improving the lives of patients? Our Lilly Oncology Discovery team has an exciting opportunity that may be a fit for you. We need a scientist who has strong technical skills in cancer cell biology. Are you eager to learn and have a high learning agility? As part of our team you will have the opportunity to participate in target identification/validation, mechanism of action (MOA) studies utilizing both genetic and pharmacological perturbation tools. This is a great opportunity to work for a company dedicated to influencing the lives of the patients we serve. We are looking for someone with these abilities:

• Design and execute molecular and cell biology experiments, troubleshoot and analyze complex data in support of Target Identification and validation projects.
• Design and conduct genetic (using RNAi and CRISPR) and pharmacological perturbation (small molecule) studies to validate oncology targets.
• Design and conduct MOA studies using basic molecular biology tools involving RNA, DNA and protein-based studies including but not limited to western blotting, taqman, gene expression studies etc.
• Design, validation and execution of cell-based assays including but not limited to flow cytometry, immunofluorescence and high content analysis.
• Perform cell culture such as transient transfections, viral expression systems and stable cell line generation.
• Perform independent analysis, processing and reporting of raw data and have the opportunity to summarize and present research to cross-functional team members within Oncology.
• Maintain high laboratory standards with regard to quality and safety

48189BR

Basic Qualifications

• BS degree in Biology or related discipline at least 1 or more years of research experience or
• MS degree in Biology or related discipline with lab research component.
• Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position.

Additional Skills/Preferences

• Knowledge of cancer biology cell signaling pathways is preferred.
• Lab experience in cancer cell biology and RNAi/CRISPR
• Extensive experience with cell culture techniques (e.g. growing cell lines, transfections, virus infection, generation of stable cell lines, etc).
• Extensive cell biology and molecular biology skills such as nucleic acid (RNA, DNA) isolation, taqman, flow cytometry, western blotting, immunoprecipitation.
• Experience and willingness to work with lentiviruses, small molecules and animal tissue
• Ability to perform quantitative analysis of data.
• Excellent oral/written communication skills and ability to work both independently and in a team environment.

Additional Information

• Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.