Scientist (Research and Development – Vivarium)

AveXis Inc.
San Diego, CA, US
Feb 13, 2019
Biotech Beach
Required Education
Bachelors Degree
Position Type
Full time

Ready to join a team committed to moving gene therapies into the clinical and commercial settings for patients and families devastated by rare neurological genetic diseases? AveXis is advancing cutting-edge science to treat rare and life-threatening genetic diseases starting with our clinical-stage, proprietary gene therapy candidate, AVXS-101 (ZOLGENSMA®). We are in the midst of an incredible journey and are looking for passionate individuals to join us on this important mission.

AveXis, Inc., a Novartis Company , is a clinical-stage gene therapy company, dedicated to developing and commercializing novel treatments for patients suffering from rare and life-threatening neurological genetic diseases. Our initial product candidate, AVXS-101, is our proprietary gene therapy product candidate currently in development for the treatment of spinal muscular atrophy, or SMA, Type 1, the leading genetic cause of infant mortality, and for the treatment of SMA Type 2. The U.S. Food and Drug Administration, or FDA, has granted AVXS-101 Orphan Drug Designation for the treatment of all types of SMA and Breakthrough Therapy Designation, as well as Fast Track Designation for the treatment of SMA Type 1. In addition to developing AVXS-101 to treat SMA Type 1 and Type 2, we also plan to develop other novel treatments for rare neurological diseases, including Rett syndrome (RTT) and a genetic form of amyotrophic lateral sclerosis (ALS) caused by mutations in the superoxide dismutase 1 (SOD1) gene.

Scientist, Research and Development is responsible for executing in vivo experiments for AveXis programs. This individual will work in the vivarium and laboratory, responsible for execution of experiments related to existing and pipeline products. This individual will report to a Senior Scientist in Research and Development.


  • Conducting in vivo studies and supporting various research projects.
  • Handling and dosing mice via multiple routes (IV, ICV, PO).
  • Assisting with breeding and maintenance of multiple transgenic mouse colonies.
  • Understanding and following standard operating procedures (SOP) and IACUC protocols.
  • Maintaining records to comply with regulatory requirements.
  • Presenting results to colleagues and senior researchers.


  • Bachelor's degree in Biology, Neuroscience, Animal Science, or related field.
  • Prior experience with handling, blood and tissue collection, clinical and behavioral observations in mice.
  • Experience dosing neonatal and adult mice via multiple routes of administration.
  • Prior laboratory experience.
  • Basic molecular biology and cell culture experience helpful.
  • Must be able to travel for additional technical training.
  • Must be able to stand for long periods of time.
  • Work will require PPE (personal protective equipment).

This position will be located out of our San Diego offices.

The level of this position will be based on the final candidate's qualifications.

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

AveXis is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, national origin, genetics, disability, age, sexual orientation or veteran status.