Research Associate, Protein Biochemist

Location
Frederick, MD, USA
Posted
Feb 12, 2019
Ref
req208
Hotbed
BioCapital
Required Education
Bachelors Degree
Position Type
Full time
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.

KEY ROLES/RESPONSIBILITIES
  • Preparation of protein and small molecule samples for SPR (surface plasmon resonance) and NMR (Nuclear Magnetic Resonance) analysis
  • Development of biochemical/biophysical assays to measure protein:protein or protein:small molecule interactions

BASIC QUALIFICATIONS
  • Possession of a Bachelor's degree from an accredited college or university according to the Council for Higher Education Accreditation. (Additional qualifying experience may be substituted for the
  • required education). Foreign degrees must be evaluated for U.S. equivalency.
  • In addition to the educational requirements, a minimum of five (5) years of experience in a protein biochemistry laboratory
  • Experience in protein biochemistry
  • Must be able to obtain and maintain a clearance

PREFERRED QUALIFICATIONS
  • Experience in preparing samples for protein NMR analysis
  • Experience with running Biacore or SPR (surface plasmon resonance) instruments.
  • Have experience with measuring protein:ligand interactions
  • Familiarity with modern protein analytical technologies such as: FPLC (Fast Protein Liquid
  • Chromatography), Dynamic Light Scattering, Circular dichroism
  • Must be highly collaborative, self-motivated, and team-oriented

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)