Manager, Biostatistics

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary:

The Biostatistics and Data Management group is looking for a Biostatistician to support Clinical Development and Exploratory Sciences. This a position with high visibility for a qualified statistician with experience in the pharmaceutical/biotechnology sector, to collaborate in cross-functional drug development teams to develop and execute innovative statistics for the development of strategy and analysis of clinical trial studies.

Responsibilities:

• The incumbent will work with the VP of the development strategy and analysis, who will select and prioritize projects, the successful candidate will assume an important role for providing statistical supports in clinical research, including providing strategic input and leadership on statistical methods, analysis and interpretation of large and complex data sets from clinical trials in various disease areas and stages, etc.

• Work with cross-functional teams to articulate drug development questions, frame statistical approaches to address those questions, and analyze the resulting data, primarily focused on supporting development strategy and analysis across therapeutic areas covering multiple pipelines within the company.

• Take initiative on statistical thinking for all aspects of the exploratory analyses, including identification of the scientific questions, development statistical plans, and interpretation and communication of the results

• Guided by projects prioritized by the VP of development strategy and analysis, identify and apply novel analysis/modeling techniques for interpreting clinical data and enhancing tools for decision making in development programs that span therapeutic areas, from early clinical to completed phase 3 clinical trials.

• Develop and maintain good working relationships with clinical scientists, therapeutic biostatisticians, and external collaborators to drive program strategies and decisions. Proactively seek inputs from other experts within and outside the group on various projects and research activities, and share technical information when appropriate.

• Maintain and expand expertise in various computing tools to leverage internal and external data sets to drive decisions. Examples of such tools include SAS, S-Plus, R, etc.

• Plan and track project activities, timelines, and resource use. Provide justification for planned resource needs. Seek to optimize resource utilization.

• Provide technical direction and mentoring to staff. Maintain awareness of industry standards and regulatory requirements and communicate within team. Encourage personal development in the context of project work. Learn and apply techniques to promote teamwork, quality, and motivation

• Develop innovative statistics methodologies or clinical trial designs for drug discovery, present at management and team meetings, co-author publications and influence the external pharmaceutical industry and regulatory environment through participation in professional associations, conferences, and publications.

Requirements:

This position requires a PhD or equivalent degree in statistics/biostatistics or related disciplines with 4+ years of experiences. Entry level candidate with outstanding academic record will also be considered, at the biostatistician level, more experienced candidates at Manager level (Level will be commensurate with experience.).

• Solid knowledge of statistical analysis methodologies and computational statistics. The ideal candidate will have an experience in statistical computing, modeling and simulation, linear and nonlinear models, and model-informed drug development

• Expertise in statistical software such as SAS and R is required.

• Knowledge of drug discovery and development and ability to integrate statistical concepts into drug discovery and development strategies.

• Must be able to work productively in a fast-paced collaborative environment, with demonstrated critical thinking skills, and effective communication and presentation skills.

• Excellent influence and leadership skills, with a track record of collaboration with scientists and researchers at Biostatistician level.

• Publications in peer reviewed statistical/medical journals

Preferred Experience:
Bayesian methodology, data mining or machine learning algorithm. Familiarity with JAGS, R -Shiny, C++ and high performance scientific computing will be a plus.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

LMR, #LI-LR1, Biostatistics, Biostats