Bristol-Myers Squibb Company

Senior Translational Research Investigator - Emerging Technology

Location
Cambridge, MA, US
Posted
Jan 19, 2019
Ref
R1512733
Required Education
Doctorate/PHD/MD
Position Type
Full time
Senior Translational Research Investigator - Emerging Technology

Cambridge, MA

Bristol-Myers Squibb R&D is a science-driven, passionate organization determined to discover, develop and deliver medicines that have the potential to transform the lives of patients and establish new standards of care in areas of high unmet need. Patients' needs and scientific discovery are our driving force. The new Bristol-Myers Squibb research site in Cambridge's Kendall Square will position our scientific team in the heart of a vibrant ecosystem of world-class science, innovation and business opportunities. Our scientists will focus on novel targets and pathways for tumors that are refractory to current Immuno-Oncology therapies. These are significant challenges that will require innovative solutions from the biopharma, biotech and academic communities.

Role / Responsibilities

We are seeking an experienced scientist to join our Translational Research group in our new state-of-the-art facility. The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment to advance the translational research efforts. The candidate will be expected to influence across the Cambridge-facing Translational Medicine and Oncology Discovery teams to drive rationale and hypothesis regarding evaluation, application and adoption of novel, cutting edge technologies and platforms to drive our translational resistance program. The ideal candidate will have leadership qualities to influence and guide a programmatic approach to implementing these solutions, whilst also always keeping a focus on the biological questions that are being addressed. This role will require the candidate to lead and leverage, interdisciplinary colleagues across the broader organization in Cambridge, Princeton and Redwood City spanning discovery, translational and clinical teams and engage extensively with KOL's in the local community as well as further afield to keep abreast of novel approaches. This candidate will be a key decision-maker in determining which new technologies and platforms will be required to elucidate key biological questions, opening opportunities to establish new insights into why some patients do not respond to IO therapies.

Qualifications
  • MD, PhD or MD/PhD in Cancer Biology, or equivalent advanced biology degree
  • Experienced scientist with 8-10+ years' of post-graduate research experience, with a minimum of 5 years in a drug discovery or translational setting
  • Minimum 3+ years' recent experience in leading scientific teams in an academic or industry setting
  • Ideally candidate will have in-depth knowledge / understanding of various mechanisms of therapeutic response and resistance utilizing in vitro , in vivo (and potentially ex vivo ) patient-derived models
  • In-depth knowledge of emerging technology trends and demonstrable skills deploying new technologies to ask biological questions in the patient setting
  • Participated in clinical studies to better characterize the molecular underpinnings of therapeutic resistance in patient cohorts and correlation with clinical outcome
  • A track record of independent critical thinking and scientific achievement demonstrated by first authorship in recent high impact publications
  • Exposure to cancer immunotherapy including immune-checkpoint blockade with knowledge of current therapeutic landscape is highly desirable
  • Experience reviewing and assessing new technology platforms and managing partnerships with biotechnology partners
  • Experience in balanced experimental design, data visualization and basic statistical analysis are desirable
  • Prior role in multidisciplinary projects and teams with ability to integrate cross-functional information, desired but not required
  • Experience with managing CRO relationships and collaborating with KOL's would be advantageous
  • Excellent interpersonal skills and ability to communicate, both written and oral effectively and efficiently within the BMS organization and with external partners/collaborators
  • Thrives in fast-paced, dynamic work environment, bringing a pro-active mentality to the role


We follow the science and we'll continue to invest in translational medicine research, deepen our understanding of disease biology and uncover insights about predictive biomarkers with the ultimate goal of making precision medicine a reality for more patients.