Translational Medicine Intern 1
Pharmacyclics is committed to the development and commercialization of novel therapies intended to improve the quality and duration of life and to resolve serious unmet medical needs for cancer patients. Pharmacyclics is a wholly-owned subsidiary of AbbVie (NYSE:ABBV), a global, research-based biopharmaceutical company. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products and a pipeline containing multiple promising new molecules that are being studied in more than 200 clinical trials for over 20 different types of cancer.
More than 1,200 Pharmacyclics and AbbVie research scientists, clinicians, marketing, operations and corporate professionals work in the San Francisco Bay Area. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. Together, we are striving to outsmart cancer.
General Position Summary/Purpose:
The successful internship candidate will work within the Translational Medicine Department performing independent laboratory research and data analysis supporting translational research. Specifically, the intern will contribute to a project assessing cell-to-cell variability using single cell gene expression technology. This project will apply data from cell clonotype and gene expression analysis to contribute to mechanism of action studies and novel biomarker discovery. Methodologies to be utilized may include sterile cell culture, flow cytometry, assay development, and statistical and bioinformatic analysis.
Key Accountabilities/Core Job Responsibilities:
- Handling of human clinical samples following internal SOP.
- Independent execution of experiments once fully trained
- Maintaining detailed records of all experiments in laboratory notebook
- Monitoring laboratory supplies and maintaining equipment in functional order
- Data collection and data management
- Weekly presentation to team and occasional presentation to the Translational Medicine Team
- Must be current MS/PhD student majoring in Biological Sciences or a related field
- Must have completed undergraduate- and/or graduate-level statistics coursework
- Be an active student in good standing at an accredited university.
- Working knowledge of cancer biology, particularly immuno-oncology, and immune cells
- Experience with a scientific programming language (R, Matlab, Python) is a bonus
- Ability to work effectively, independently, and in a collaborative environment
- Strong interpersonal skills and communication skills
Each Intern is expected to prepare a short presentation to their team to share what they have learned through their internship and how they hope their new knowledge will help them secure their future career. Presentations may be approximately 10-15 minutes long and should include visual aid (posters or PowerPoint.
Equal Opportunity Employer Minorities/Women/Veterans/Disabled