Scientist, Oncology & Discovery

Location
Seattle, WA
Posted
Jan 18, 2019
Required Education
Doctorate/PHD/MD
Position Type
Full time

Tumor Microenvironment and Immunotherapy specialist

Join bluebird bio’s Seattle-based Oncology & Discovery group to help bring innovative cell therapy products into the clinic. In this role, you will contribute to the preclinical development of CAR and TCR cell therapies. Your background in tumor microenvironment, automation, or immunology will help to design and implement creative solutions to complex cell therapy and gene editing questions.

About the role:

  • Vocal leader with a willingness and ability to question existing scientific approaches
  • Design new approaches to improve efficacy of cellular therapeutics, including overcoming tumor microenvironment, T cell exhaustion or antigen escape
  • Work together with associate scientists, project leaders and other groups across bluebird bio to drive project success

 About you:

  • PhD in Immunology, Cell Biology, Molecular Biology, Bioengineering, or a related discipline. Post-doctoral experience welcome but not required
  • Able to think creatively and independently and adapt to a fast paced and always changing work environment
  • Thorough understanding of immunology and tumor microenvironment, including factors driving T cell exhaustion, antigen escape, and immunosuppression.
  • Excellent communications skills and ability to manage projects with internal and external collaborators
  • Familiarity with using automation and robotics in preclinical screening. Knowledge of Hamilton liquid handlers, is a plus but not required.
  • Strong technical background with standard laboratory methods, including: polychromatic flow cytometry; molecular biology and cloning; lentivirus and adeno associated virus handling and production; PCR; ELISA; intracellular staining;
  • Very organized and diligent in experimental design, execution, and reporting
  • Be ready to embrace the principles of the bluebird bio culture:  b colorful, b cooperative, and b yourself