Senior Principal Scientist, GI Immunology

The Immunology Discovery organization is responsible for identification of new therapeutic approaches for the treatment of autoimmune diseases. We have an exciting opportunity for a Senior Principal Scientist based in Worcester, MA reporting to the Director of Pharmacology.

We are seeking a dynamic and innovative leader to guide the development and implementation of mechanism of action, PK/PD, biomarker and pharmacology assessments across a range of preclinical approaches. Expert knowledge in immunology, especially IBD/GI Disease, and the design and conduct of both in vitro and in vivo models of autoimmunity and inflammation are essential.

The successful candidate will lead a group of scientists in the Immunology Pharmacology Department. Some of the responsibilities include:

• Provide strong scientific, technical, and organizational leadership to drive IBD/GI disease drug discovery and related immunology disease areas.
• Provide detailed knowledge of the pathophysiologic mechanisms of IBD/GI disease and apply this knowledge to implement new concepts and methodologies for the development of drug candidates.
• Drive excellent performance of group by effectively managing both direct and indirect reports including recruiting, managing, mentoring and developing scientific staff
• Contribute to defining research team goals by collaborating with scientists within and outside functional area

Position will be hired based on level of experience.

• BS, MS, PhD or DVM in biological sciences with 18+ (BS), 16+(MS, or 10+ (PhD) years of postdoc/industry experience
• Established track record of delivering multiple candidates to development
• Recognized leader in pharmacology with in-depth knowledge of in vitro assay systems and disease models and ability to establish PK/PD correlates
• Experience in managing direct reports and development of scientific staff with positive team building and teamwork skills
• Evidence of strategic thinking and portfolio management a plus
• Ability to manage and maintain scientific business relationships and contract research agreements
• Strong written and oral communication skills
• Outstanding track record of publications

Equal Opportunity Employer Minorities/Women/Veterans/Disabled