Scientist l, New Biological Entities

Lake County, IL, US
Jan 11, 2019
Required Education
Bachelors Degree
Position Type
Full time
The pharmaceutical development group for new biological entities (NBEs) develops antibody drug conjugates (ADC) and other biologics by state of the art formulation and analytical technologies. We create intellectual property through new formulation compositions, cost effective manufacturing processes and prepare and defend CMC (Chemistry, Manufacturing and Control) regulatory content.

We are looking for a highly motivated person who supports analytical development and routine testing of NBEs. The candidate will identify, investigate and implement novel experimental approaches to answer scientific questions to develop and optimize NBE drug product formulations. Working closely with formulation and process development scientists, the candidate will d evelop productive collaborations and communications with scientific teams.

Section I: Major Responsibilities:

  • Analytical characterization and assessment of formulation development samples and clinical trial supplies (e.g. GMP compliant stability and release testing)
  • Execute and design experiments for method development and validation studies
  • Documents experimental data appropriately in laboratory documentation system and technical memos; contributes to writing technical reports.
  • Maintains laboratory equipment and optimize laboratory operations for efficient use of time and resources.
  • Lead troubleshooting of equipment and experimental problems.
  • Brainstorm ideas for continuous improvement activities and leads initiative.
  • Responsible for compliance with all applicable AbbVie policies and procedures.
  • Understand and adhere to corporate standards regarding code of conduct, safety, and GXP compliance.

Level will be based on education and years of experience.
  • BS (5+ years) or MS (2+ years) in scientific discipline (e.g., Chemistry, Biochemistry, or Biology) with previous laboratory experience
  • Experience in analytical methodology, such as chromatography, KF, UV and compendial methods. Experience in bioanalytical techniques preferred (WCX, HIC, SEC, CGE, icIEF, particle imaging, ELISA and LC-MS).
  • Experienced in laboratory systems (LIMS, CDS, ELN) preferred.
  • Experience in Microsoft Office (Excel, Power Point, and Word) required.
  • Statistical knowledge and experience is preferred e.g. capability analysis, gauge R&R and design of experiments (DOE) methodologies

Key AbbVie Competencies:
  • Builds strong relationships with peers and cross functionally with partners outside of teams to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Equal Opportunity Employer Minorities/Women/Veterans/Disabled