Eli Lilly and Company

Research Scientist-Quantitative Systems Pharmacology/Pharmacometrician

Location
Indianapolis, IN, United States
Posted
Jan 09, 2019
Ref
47340
Required Education
Masters Degree/MBA
Position Type
Full time
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Responsibilities
The scientists in the department of PK/PD & Pharmacometrics at Lilly are the leaders in research and development throughout the value chain from preclinical lead molecule identification to clinical post-drug approval with the goal of identifying and developing the right drug with the right dose for the right patient and living the model-informed paradigm of drug research and development. Our organization is looking for a dynamic scientist who will be responsible for :
  • Implementing Pharmacometrics and Quantitative System Pharmacology modeling and simulation techniques to address key questions and influence portfolio decisions, including, but not limited to the application of drug-disease models, literature models, quantitative risk/benefit decision tools, quantitative systems pharmacology models and trial-design optimization analytics.
  • Contributing to the development of novel QSP platform(s) for various disease states and improving existing QSP platforms.
  • Anticipating and recognizing the issues affecting the drug discovery/development and finding effective solutions by partnership and collaboration with cross-functional teams to enable decision-making.
  • Providing scientific expertise in multi-disciplinary project teams to support the selection of the right target, molecule, dose, patient population and development strategies.
  • Actively contribute to team by engaging with fellow scientists within the group and in other disciplines as well as interact, teach and collaborate with scientists in academia.
  • Representing the group to increase visibility externally, through key publications, active leadership in key scientific organizations, industry trade groups or consortia.
In summary, in this exciting scientific and technical role you will have opportunities to apply MIDD principles to drug research and development strategies, help set direction for the organization, and drive successful implementation of the strategies to produce results.

47340BR

Basic Qualifications
  • Master's or advanced degree in relevant scientific discipline such as biological/pharmaceutical sciences, bioengineering or related field with 8 years of relevant experience or
  • PhD and/or MD in relevant scientific field such as biological/pharmaceutical sciences, bioengineering or related field.
  • Experience in quantitative pharmacology modeling is highly preferred.


Additional Skills/Preferences
  • Excellent understanding of systems pharmacology principles.
  • Proficient in quantitative modeling and simulation software (such as SimBiology, NONMEM, MATLAB, R/S-plus etc.).
  • Work effectively in a team environment with excellent communication skills.


Additional Information
  • This position can be located either in Indianapolis, US or Erlwood, UK site.
  • Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.