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Scientist, NCI Patient Derived Models Repository Distribution Quality Control Manager

Employer
Frederick National Laboratory for Cancer Research
Location
Frederick, MD, USA
Start date
Dec 22, 2018

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Discipline
Manufacturing & Production, Quality, Science/R&D, Biotechnology
Required Education
Doctorate/PHD/MD
Position Type
Full time
Hotbed
BioCapital
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Job Details

The Applied and Developmental Research Directorate (ADRD) provides clinical and biological monitoring, regulatory support, biospecimen processing and storage, assay development, and project management support to the National Cancer Institute (NCI) and National Institute of Allergy and Infectious Disease(NIAID) clinical programs, including the Division of Cancer Treatment and Diagnosis (DCTD). The NCI Patient Derived Models Repository (PDMR) provides scientific and logistical support for all aspects of patient-derived model development including tissue and clinical data acquisition, model development, model quality control and quality assurance, and model distribution.

KEY ROLES/RESPONSIBILITIES

The Scientist II, NCI Patient Derived Models Repository Distribution Quality Control Manager, will:
  • Provide scientific oversight for data accuracy and quality control of all in vivo, in vitro, and organoid models being developed for internal and public distribution by NCI's Patient Derived Models Repository (PDMR)
  • Assist the PDMR Operations Manager in pathology and nextgen sequencing data review and QC for upcoming distributable models and help focus efforts of a multi-laboratory program for high-priority models and data review
  • Perform scientific QC review of data in Certificates of Analysis for distributable in vitro and organoid cultures
  • Oversee and track progress for internal projects utilizing patient-derived models
  • Create and update standard operating procedures (sops) to keep up with a fast-paced and evolving workflow

BASIC QUALIFICATIONS
  • Possession of a Doctoral degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical research. (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency.
  • In addition to educational requirements, have at least two (2) years of experience in an in vitro or in vivo laboratory; post-doctoral training or experience is required for this position
  • Must be able to obtain and maintain a security clearance
  • Strong organizational and communication skills (written and oral) and ability to author documents including manuscripts for publications, SOPs, clinical protocols, etc.
  • Proficient with Microsoft Office (Excel, Word, and PowerPoint)

PREFERRED QUALIFICATIONS
  • Hands-on experience developing or validating patient derived xenograft or in vitro culture models
  • Experience with SharePoint and SQL or Oracle databases
  • Experience with R, SigmaPlot, GraphPad Prism
  • Ability to work effectively in a team‐oriented environment
  • Ability to identify and solve complex problems
  • Strong multitasking skills

Expected Competencies:
  • Ability to collaborate with a diverse group of scientific staff responsible for data review and quality assessment.
  • Outstanding English language communication skills are required
  • Ability to communicate with program lead researchers in a demanding scientific environment through preparation of formal reports and presentations
  • A record of publication in refereed scientific literature

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

Company

A rewarding career with global impact

Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.

Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.

We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.

Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.

Discover why joining the Frederick National Laboratory team could be the most important career step you take

 

 

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Company info
Website
Phone
301-846-1000
Location
8560 Progress Drive
 Frederick
MD
21701
US
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