Bristol-Myers Squibb Company

Research Investigator I/II (Cancer Genetics Focused)

Cambridge, MA, US
Dec 08, 2018
Required Education
Position Type
Full time
The Research Investigator will join the Immuno Oncology Resistance Biology research team at Bristol-Myers Squibb (BMS) in Cambridge, MA. This team is composed of cancer biologists, cancer geneticists, immunologists and immuno oncologists who work to develop therapies to address mechanisms of resistance to BMS immune oncology agents.

The qualified candidate is a highly motivated, interactive, and creative individual who possesses substantial experience in studying tumor biology and genetics, especially with respect to how these features impact immune responses to the tumor. The candidate will be expected to contribute to the team's project portfolio by developing new project hypotheses (gleaned from literature reports, evaluation of public and proprietary tumor profiling datasets, preclinical mechanistic models and screens, etc.), validate the hypothesis in preclinical models, and develop assays to support early preclinical drug development. The opportunity to gain experience in preclinical drug development is available as successful hypotheses progress into later stages of preclinical development. The highly matrixed organization also provides the opportunity for the successful candidate to broaden their scientific expertise into immunology and immune oncology.

The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams, senior management and at external scientific meetings. The candidate will contribute to the development of external partnerships/collaborations to advance internal programs and the understanding of the interplay between tumor genetics/biology and anti-tumor immune responses as well as publish to advance our science and support our scientific reputation. As a highly matrixed working group, the individual should demonstrate the ability to contribute to various projects outside of his/her own, as appropriate, and collaborate with stakeholders from all relevant and necessary functions within BMS. S/he will keep up-to-date in the literature related to his/her field, act as an expert resource in his/her scientific field and in related disciplines.


A Ph.D. degree with 6+ years post-doctoral/academic/industrial experience in cancer biology and genetics or a closely related field is required. A proven track record in the field of cancer biology and genetics, as evidenced by publication record is required. Excellent in vitro biology skills, experimental design and execution is required, as is expertise to independently apply bioinformatics and data mining through multi-variate analysis; ability to effectively interact with core bioinformatics colleagues, as well as to use desktop tools/interfaces (e.g., Oncoland, Wuxi) and public databases (CBIO, Achilles, etc.) is required. Experience in the design, validation and execution of genetic and/or phenotypic screens is desired. Excellent interpersonal skills with the ability to interact and influence effectively with people, internally and externally, is required. The ability to manage a small laboratory group is expected, including providing from growth and development opportunities for associates reports. This position is located in Cambridge, MA. There will be less than 10% travel.