Temp Associate Scientist Oncology and Angiogenesis
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary The Oncology and Angiogenesis team is seeking a highly skilled Scientist to contribute to the discovery and validation of therapeutic cancer targets and development of anti-tumor therapeutic antibodies that engage the immune system. The successful candidate will conduct preclinical in vivo experiments as well as advanced in vitro assays. The qualified candidate will have a background in immunology and/or oncology and will be familiar with techniques such as flow cytometry, cell culture, and murine tumor models. The candidate must be highly motivated and organized with efficient time management, attention to detail, and is expected to effectively and frequently communicate and collaborate with colleagues. Responsibilities include, but are not limited to . Properly handle and care for mice, intra-peritoneal injection and collect blood and tissue samples . Experienced in isolation and characterization of primary immune cells from murine tissues and human blood is a plus . Experienced in cell culture both primary cells and established cell lines and transfection . experience with viral transduction is a plus . Intermediate level of understanding and experience with flow cytometry assays . Analyze data using biological and statistical software, such as Flowjo, Prism, Excel, etc . Document experimental procedures and results in a well-organized fashion . generate experimental reports . Participate in general lab duties of the team - Additionally, the successful candidate should be receptive to novel technologies to increase work efficiency, optimization of current protocols and development of new techniques . Requirements TECHNICAL SKILLS REQUIRED - Knowledge of basic cellular and molecular immunology - Experience in the isolation and characterization of primary immune cells from murine tissues/tumors and/or human blood - Skilled in a variety of in vitro/ex vivo immune cell-based assays, including planning, execution, analysis and record keeping - Intermediate knowledge and practical experience with advanced flow cytometry, including cell surface staining, intracellular staining, data acquisition and analysis. Experience in panel design is a plus - Expertise with animal handling is a must . experienced in different methods of compound administration i.v , i.p , s.c , etc , and tissue /sample collection - Ability to design and perform complex in vivo experiments utilizing tumor models in mice - Experience with recombinant lentiviral vectors and antibody technology or development is a plus - Experience with T cells, DC/macrophage-based functional assays is highly preferred. CORE COMPETENCIES - Strong organizational and time-management skills including the ability to handle multiple tasks simultaneously and prioritize - Demonstrated creativity and independency - Ability to effectively collaborate as part of cross-functional teams - Clear and professional verbal and written communication . Minimum Years of Experience . This position requires a PhD and 0 years postdoctoral experience. This position will require the individual to pass a physical before beginning employment. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies . Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.